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GRM1 glutamate metabotropic receptor 1 [ Homo sapiens (human) ]

Gene ID: 2911, updated on 6-Dec-2016
Official Symbol
GRM1provided by HGNC
Official Full Name
glutamate metabotropic receptor 1provided by HGNC
Primary source
HGNC:HGNC:4593
See related
Ensembl:ENSG00000152822 MIM:604473; Vega:OTTHUMG00000015752
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MGLU1; GPRC1A; MGLUR1; SCAR13; PPP1R85
Summary
This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Orthologs
Location:
6q24.3
Exon count:
11
Annotation release Status Assembly Chr Location
108 current GRCh38.p7 (GCF_000001405.33) 6 NC_000006.12 (146027634..146437598)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (146286032..146758782)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100507557 Neighboring gene uncharacterized LOC105378039 Neighboring gene F-box protein 30 Neighboring gene SNF2 histone linker PHD RING helicase Neighboring gene FUN14 domain containing 2 pseudogene 3 Neighboring gene RNA, 5S ribosomal pseudogene 222 Neighboring gene uncharacterized LOC101928661 Neighboring gene RAB32, member RAS oncogene family

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Protein interactions

Protein Gene Interaction Pubs
Tat tat HIV-1 Tat upregulates N-methyl-D-aspartate receptor function by activating metabotropic glutamate receptor 1 in human brain noradrenergic neurons PubMed
tat HIV-1 Tat potentiates the depolarization-evoked exocytosis of aspartate from human neocortical terminals, which involves the metabotropic glutamate (mGlu) 1 receptor PubMed

Go to the HIV-1, Human Interaction Database

  • Calcium signaling pathway, organism-specific biosystem (from KEGG)
    Calcium signaling pathway, organism-specific biosystemCa2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this...
  • Calcium signaling pathway, conserved biosystem (from KEGG)
    Calcium signaling pathway, conserved biosystemCa2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this...
  • Class C/3 (Metabotropic glutamate/pheromone receptors), organism-specific biosystem (from REACTOME)
    Class C/3 (Metabotropic glutamate/pheromone receptors), organism-specific biosystemThe class C G-protein-coupled receptors are a class of G-protein coupled receptors that include the metabotropic glutamate receptors and several additional receptors (Brauner-Osborne H et al, 2007). ...
  • Common Pathways Underlying Drug Addiction, organism-specific biosystem (from WikiPathways)
    Common Pathways Underlying Drug Addiction, organism-specific biosystemThe pathway was modeled after Figure 2 in Li, et al. 2008 and is based on the common pathways identified in their study as well as protein interaction data. Specifically, glutamate and dopamine neuro...
  • ERK Pathway in Huntington's Disease, organism-specific biosystem (from WikiPathways)
    ERK Pathway in Huntington's Disease, organism-specific biosystemThis ERK pathway is implicated in Huntington's Disease. The ligands BDNF, EGF, and Glu bind to their respective receptors (TrkB, EGFR, mGluR) and start a signal transduction pathway starting with RAS...
  • Estrogen signaling pathway, organism-specific biosystem (from KEGG)
    Estrogen signaling pathway, organism-specific biosystemEstrogens are steroid hormones that regulate a plethora of physiological processes in mammals, including reproduction, cardiovascular protection, bone integrity, cellular homeostasis, and behavior. E...
  • Estrogen signaling pathway, conserved biosystem (from KEGG)
    Estrogen signaling pathway, conserved biosystemEstrogens are steroid hormones that regulate a plethora of physiological processes in mammals, including reproduction, cardiovascular protection, bone integrity, cellular homeostasis, and behavior. E...
  • FoxO signaling pathway, organism-specific biosystem (from KEGG)
    FoxO signaling pathway, organism-specific biosystemThe forkhead box O (FOXO) family of transcription factors regulates the expression of genes in cellular physiological events including apoptosis, cell-cycle control, glucose metabolism, oxidative str...
  • G alpha (q) signalling events, organism-specific biosystem (from REACTOME)
    G alpha (q) signalling events, organism-specific biosystemThe classic signalling route for G alpha (q) is activation of phospholipase C beta thereby triggering phosphoinositide hydrolysis, calcium mobilization and protein kinase C activation. This provides ...
  • GPCR downstream signaling, organism-specific biosystem (from REACTOME)
    GPCR downstream signaling, organism-specific biosystemG protein-coupled receptors (GPCRs) are classically defined as the receptor, G-protein and downstream effectors, the alpha subunit of the G-protein being the primary signaling molecule. However, it h...
  • GPCR ligand binding, organism-specific biosystem (from REACTOME)
    GPCR ligand binding, organism-specific biosystemThere are more than 800 G-protein coupled receptor (GPCRs) in the human genome, making it the largest receptor superfamily. GPCRs are also the largest class of drug targets, involved in virtually all...
  • GPCRs, Class C Metabotropic glutamate, pheromone, organism-specific biosystem (from WikiPathways)
    GPCRs, Class C Metabotropic glutamate, pheromone, organism-specific biosystemThis pathway was created using the GPCRDB (Horn et al., 1998), http://www.gpcr.org/7tm/ (originally at http://www.cmbi.kun.nl/7tm/). The groupings are based on the GPCR phylogenetic tree available fr...
  • GPCRs, Other, organism-specific biosystem (from WikiPathways)
    GPCRs, Other, organism-specific biosystemThis pathway was created using the GPCRDB (Horn et al., 1998), http://www.gpcr.org/7tm/ (originally at http://www.cmbi.kun.nl/7tm/). The groupings are based on the GPCR phylogenetic tree available fr...
  • Gap junction, organism-specific biosystem (from KEGG)
    Gap junction, organism-specific biosystemGap junctions contain intercellular channels that allow direct communication between the cytosolic compartments of adjacent cells. Each gap junction channel is formed by docking of two 'hemichannels'...
  • Gap junction, conserved biosystem (from KEGG)
    Gap junction, conserved biosystemGap junctions contain intercellular channels that allow direct communication between the cytosolic compartments of adjacent cells. Each gap junction channel is formed by docking of two 'hemichannels'...
  • Gastrin-CREB signalling pathway via PKC and MAPK, organism-specific biosystem (from REACTOME)
    Gastrin-CREB signalling pathway via PKC and MAPK, organism-specific biosystemGastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic fac...
  • Glutamatergic synapse, organism-specific biosystem (from KEGG)
    Glutamatergic synapse, organism-specific biosystemGlutamate is the major excitatory neurotransmitter in the mammalian central nervous system(CNS). Glutamate is packaged into synaptic vesicles in the presynaptic terminal. Once released into the synap...
  • Glutamatergic synapse, conserved biosystem (from KEGG)
    Glutamatergic synapse, conserved biosystemGlutamate is the major excitatory neurotransmitter in the mammalian central nervous system(CNS). Glutamate is packaged into synaptic vesicles in the presynaptic terminal. Once released into the synap...
  • Interactions of neurexins and neuroligins at synapses, organism-specific biosystem (from REACTOME)
    Interactions of neurexins and neuroligins at synapses, organism-specific biosystemNeurexins (NRXNs) and neuroligins (NLGNs) are best characterized synaptic cell-adhesion molecules. They are part of excitatory glutamatergic and inhibitory GABAergic synapses in mammalian brain, medi...
  • Long-term depression, organism-specific biosystem (from KEGG)
    Long-term depression, organism-specific biosystemCerebellar long-term depression (LTD), thought to be a molecular and cellular basis for cerebellar learning, is a process involving a decrease in the synaptic strength between parallel fiber (PF) and...
  • Long-term depression, conserved biosystem (from KEGG)
    Long-term depression, conserved biosystemCerebellar long-term depression (LTD), thought to be a molecular and cellular basis for cerebellar learning, is a process involving a decrease in the synaptic strength between parallel fiber (PF) and...
  • Long-term potentiation, organism-specific biosystem (from KEGG)
    Long-term potentiation, organism-specific biosystemHippocampal long-term potentiation (LTP), a long-lasting increase in synaptic efficacy, is the molecular basis for learning and memory. Tetanic stimulation of afferents in the CA1 region of the hippo...
  • Long-term potentiation, conserved biosystem (from KEGG)
    Long-term potentiation, conserved biosystemHippocampal long-term potentiation (LTP), a long-lasting increase in synaptic efficacy, is the molecular basis for learning and memory. Tetanic stimulation of afferents in the CA1 region of the hippo...
  • Neuroactive ligand-receptor interaction, organism-specific biosystem (from KEGG)
    Neuroactive ligand-receptor interaction, organism-specific biosystem
    Neuroactive ligand-receptor interaction
  • Neuroactive ligand-receptor interaction, conserved biosystem (from KEGG)
    Neuroactive ligand-receptor interaction, conserved biosystem
    Neuroactive ligand-receptor interaction
  • Neuronal System, organism-specific biosystem (from REACTOME)
    Neuronal System, organism-specific biosystemThe human brain contains at least 100 billion neurons, each with the ability to influence many other cells. Clearly, highly sophisticated and efficient mechanisms are needed to enable communication a...
  • Phospholipase D signaling pathway, organism-specific biosystem (from KEGG)
    Phospholipase D signaling pathway, organism-specific biosystemPhospholipase D (PLD) is an essential enzyme responsible for the production of the lipid second messenger phosphatidic acid (PA), which is involved in fundamental cellular processes, including membra...
  • Phospholipase D signaling pathway, conserved biosystem (from KEGG)
    Phospholipase D signaling pathway, conserved biosystemPhospholipase D (PLD) is an essential enzyme responsible for the production of the lipid second messenger phosphatidic acid (PA), which is involved in fundamental cellular processes, including membra...
  • Protein-protein interactions at synapses, organism-specific biosystem (from REACTOME)
    Protein-protein interactions at synapses, organism-specific biosystemSynapses constitute highly specialized sites of asymmetric cell-cell adhesion and intercellular communication. Its formation involves the recruitment of presynaptic and postsynaptic molecules at newl...
  • Retrograde endocannabinoid signaling, organism-specific biosystem (from KEGG)
    Retrograde endocannabinoid signaling, organism-specific biosystemEndogenous cannabinoids (endocannabinoids) serve as retrograde messengers at synapses in various regions of the brain. The family of endocannabinoids includes at least five derivatives of arachidonic...
  • Retrograde endocannabinoid signaling, conserved biosystem (from KEGG)
    Retrograde endocannabinoid signaling, conserved biosystemEndogenous cannabinoids (endocannabinoids) serve as retrograde messengers at synapses in various regions of the brain. The family of endocannabinoids includes at least five derivatives of arachidonic...
  • Signal Transduction, organism-specific biosystem (from REACTOME)
    Signal Transduction, organism-specific biosystemSignal transduction is a process in which extracellular signals elicit changes in cell state and activity. Transmembrane receptors sense changes in the cellular environment by binding ligands, such a...
  • Signaling by GPCR, organism-specific biosystem (from REACTOME)
    Signaling by GPCR, organism-specific biosystemG protein-coupled receptors (GPCRs; 7TM receptors; seven transmembrane domain receptors; heptahelical receptors; G protein-linked receptors [GPLR]) are the largest family of transmembrane receptors i...
  • Taste transduction, organism-specific biosystem (from KEGG)
    Taste transduction, organism-specific biosystemFive basic tastes are recognized by humans and most other animals - bitter, sweet, sour, salty and umami. In vertebrates, taste stimuli are detected by taste receptor cells (TRCs). At least three dis...
  • Taste transduction, conserved biosystem (from KEGG)
    Taste transduction, conserved biosystemFive basic tastes are recognized by humans and most other animals - bitter, sweet, sour, salty and umami. In vertebrates, taste stimuli are detected by taste receptor cells (TRCs). At least three dis...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
G-protein coupled receptor activity TAS
Traceable Author Statement
more info
PubMed 
glutamate receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
glutamate receptor activity TAS
Traceable Author Statement
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
G-protein coupled receptor dimeric complex IDA
Inferred from Direct Assay
more info
PubMed 
G-protein coupled receptor homodimeric complex IPI
Inferred from Physical Interaction
more info
PubMed 
dendrite IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
plasma membrane TAS
Traceable Author Statement
more info
 
postsynaptic density IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
metabotropic glutamate receptor 1
Names
glutamate receptor, metabotropic 1
protein phosphatase 1, regulatory subunit 85

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012839.1 RefSeqGene

    Range
    5001..414953
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001278064.1NP_001264993.1  metabotropic glutamate receptor 1 isoform alpha precursor

    See identical proteins and their annotated locations for NP_001264993.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) encodes the longest isoform (alpha).
    Source sequence(s)
    AB208837, BC136280, L76627, L76631
    Consensus CDS
    CCDS5209.1
    UniProtKB/Swiss-Prot
    Q13255
    UniProtKB/TrEMBL
    Q59HC2
    Related
    ENSP00000282753, OTTHUMP00000017365, ENST00000282753, OTTHUMT00000042574
    Conserved Domains (5) summary
    cd06374
    Location:36510
    PBP1_mGluR_groupI; Ligand binding domain of the group I metabotropic glutamate receptor
    pfam00003
    Location:604837
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:77485
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:521570
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    pfam10606
    Location:11441194
    GluR_Homer-bdg; Homer-binding domain of metabotropic glutamate receptor
  2. NM_001278065.1NP_001264994.1  metabotropic glutamate receptor 1 isoform beta precursor

    See identical proteins and their annotated locations for NP_001264994.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) contains an alternate exon in the 3' coding region, compared to variant 3. The encoded isoform (beta) is shorter and contains a distinct C-terminus, compared to isoform alpha. Isoform beta has a different subcellular distribution than isoform alpha and may be functionally distinct due to differential G-protein coupling of its novel C-terminal sequence (PMID: 9076744). Variants 4 and 5 encode the same isoform.
    Source sequence(s)
    AB208837, L76627, L76631
    Consensus CDS
    CCDS47497.1
    UniProtKB/Swiss-Prot
    Q13255
    UniProtKB/TrEMBL
    Q59HC2
    Related
    ENSP00000424095, OTTHUMP00000017366, ENST00000492807, OTTHUMT00000042575
    Conserved Domains (4) summary
    cd06374
    Location:36510
    PBP1_mGluR_groupI; Ligand binding domain of the group I metabotropic glutamate receptor
    pfam00003
    Location:604837
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:77485
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:521570
    NCD3G; Nine Cysteines Domain of family 3 GPCR
  3. NM_001278066.1NP_001264995.1  metabotropic glutamate receptor 1 isoform beta precursor

    See identical proteins and their annotated locations for NP_001264995.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) contains an alternate internal exon in the 3' coding region and uses an alternate splice site in the 3'-terminal exon, compared to variant 3. The encoded isoform (beta) is shorter and contains a distinct C-terminus, compared to isoform alpha. Isoform beta has a different subcellular distribution than isoform alpha and may be functionally distinct due to differential G-protein coupling of its novel C-terminal sequence (PMID: 9076744). Variants 4 and 5 encode the same isoform.
    Source sequence(s)
    AB208837, BC143777, L76627, L76631
    Consensus CDS
    CCDS47497.1
    UniProtKB/Swiss-Prot
    Q13255
    UniProtKB/TrEMBL
    Q59HC2
    Related
    ENSP00000425599, OTTHUMP00000222176, ENST00000507907, OTTHUMT00000369232
    Conserved Domains (4) summary
    cd06374
    Location:36510
    PBP1_mGluR_groupI; Ligand binding domain of the group I metabotropic glutamate receptor
    pfam00003
    Location:604837
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:77485
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:521570
    NCD3G; Nine Cysteines Domain of family 3 GPCR
  4. NM_001278067.1NP_001264996.1  metabotropic glutamate receptor 1 isoform d precursor

    See identical proteins and their annotated locations for NP_001264996.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 3. The encoded isoform (d) is shorter and contains a distinct C-terminus, compared to isoform alpha. Isoform d may have a distinct function compared to isoform alpha (PMID: 9776379).
    Source sequence(s)
    AB208837, BC143779, L76627, L76631
    Consensus CDS
    CCDS64548.1
    UniProtKB/Swiss-Prot
    Q13255
    UniProtKB/TrEMBL
    Q59HC2
    Related
    ENSP00000347437, OTTHUMP00000222175, ENST00000355289, OTTHUMT00000369231
    Conserved Domains (4) summary
    cd06374
    Location:36510
    PBP1_mGluR_groupI; Ligand binding domain of the group I metabotropic glutamate receptor
    pfam00003
    Location:604837
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:77485
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:521570
    NCD3G; Nine Cysteines Domain of family 3 GPCR

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p7 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p7 Primary Assembly

    Range
    146027634..146437598
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017010784.1XP_016866273.1  

    UniProtKB/Swiss-Prot
    Q13255
    Related
    ENSP00000354896, ENST00000361719
    Conserved Domains (5) summary
    cd06374
    Location:36510
    PBP1_mGluR_groupI; Ligand binding domain of the group I metabotropic glutamate receptor
    pfam00003
    Location:604837
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:77485
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:521570
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    pfam10606
    Location:11441194
    GluR_Homer-bdg; Homer-binding domain of metabotropic glutamate receptor
  2. XM_017010783.1XP_016866272.1  

    UniProtKB/Swiss-Prot
    Q13255
    Conserved Domains (5) summary
    cd06374
    Location:36510
    PBP1_mGluR_groupI; Ligand binding domain of the group I metabotropic glutamate receptor
    pfam00003
    Location:604837
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:77485
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:521570
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    pfam10606
    Location:11441194
    GluR_Homer-bdg; Homer-binding domain of metabotropic glutamate receptor
  3. XM_017010787.1XP_016866276.1  

    UniProtKB/Swiss-Prot
    Q13255
    Conserved Domains (4) summary
    cd06374
    Location:36510
    PBP1_mGluR_groupI; Ligand binding domain of the group I metabotropic glutamate receptor
    pfam00003
    Location:604837
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:77485
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:521570
    NCD3G; Nine Cysteines Domain of family 3 GPCR
  4. XM_017010785.1XP_016866274.1  

    UniProtKB/Swiss-Prot
    Q13255
    Conserved Domains (4) summary
    cd06374
    Location:36510
    PBP1_mGluR_groupI; Ligand binding domain of the group I metabotropic glutamate receptor
    pfam00003
    Location:604837
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:77485
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:521570
    NCD3G; Nine Cysteines Domain of family 3 GPCR
  5. XM_017010786.1XP_016866275.1  

    UniProtKB/Swiss-Prot
    Q13255
    Conserved Domains (4) summary
    cd06374
    Location:36510
    PBP1_mGluR_groupI; Ligand binding domain of the group I metabotropic glutamate receptor
    pfam00003
    Location:604837
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:77485
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:521570
    NCD3G; Nine Cysteines Domain of family 3 GPCR
  6. XM_011535782.1XP_011534084.1  

    See identical proteins and their annotated locations for XP_011534084.1

    UniProtKB/Swiss-Prot
    Q13255
    Conserved Domains (5) summary
    cd06374
    Location:36510
    PBP1_mGluR_groupI; Ligand binding domain of the group I metabotropic glutamate receptor
    pfam00003
    Location:604837
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:77485
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:521570
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    pfam10606
    Location:11441194
    GluR_Homer-bdg; Homer-binding domain of metabotropic glutamate receptor
  7. XM_017010788.1XP_016866277.1  

Alternate CHM1_1.1

Genomic

  1. NC_018917.2 Alternate CHM1_1.1

    Range
    146612129..147021949
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_000838.3: Suppressed sequence

    Description
    NM_000838.3: This RefSeq was based on transcripts that have no full-length support, compared to the NM_001278064.1, which is also valid for CCDS5209.1. Therefore, NM_001114329.1 is suppressed, but the CCDS ID is retained for the other variant.
  2. NM_001114329.1: Suppressed sequence

    Description
    NM_001114329.1: This RefSeq was based on transcripts that have no full-length support, compared to NM_001278065.1, which is also valid for CCDS47497.1. Therefore, NM_001114329.1 is suppressed, but the CCDS ID is retained for the other variant.
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