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Snrnp48 small nuclear ribonucleoprotein U11/U12 subunit 48 [ Rattus norvegicus (Norway rat) ]

Gene ID: 291060, updated on 3-Jun-2026
Official Symbol
Snrnp48provided by RGD
Official Full Name
small nuclear ribonucleoprotein U11/U12 subunit 48provided by RGD
Primary source
RGD:1309020
See related
Ensembl:ENSRNOG00000013756 AllianceGenome:RGD:1309020
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309020
Summary
Predicted to enable zinc ion binding activity. Predicted to be part of U12-type spliceosomal complex. Predicted to be active in cytosol and nucleoplasm. Orthologous to human SNRNP48 (small nuclear ribonucleoprotein U11/U12 subunit 48). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Thymus (RPKM 107.2), Lung (RPKM 93.4) and 9 other tissues See more
Orthologs
all
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See Snrnp48 in Genome Data Viewer
Location:
17p12
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (26801818..26821605, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (26596266..26616058, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (27243732..27279271, complement)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene thioredoxin domain containing 5 Neighboring gene bone morphogenetic protein 6 Neighboring gene U6 spliceosomal RNA Neighboring gene desmoplakin

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. Will CL, et al. RNA, 2004 Jun. PMID 15146077, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
part_of U12-type spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U12-type spliceosomal complex ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
Preferred Names
U11/U12 small nuclear ribonucleoprotein 48 kDa protein
Names
small nuclear ribonucleoprotein 48 (U11/U12)
small nuclear ribonucleoprotein 48k (U11/U12)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106107.2 → NP_001099577.1  U11/U12 small nuclear ribonucleoprotein 48 kDa protein isoform 1

    See identical proteins and their annotated locations for NP_001099577.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000017
    UniProtKB/TrEMBL
    A0ABK0M5K2, A6J7A8
    Conserved Domains (1) summary
    pfam05253
    Location:57 → 79
    zf-U11-48K; U11-48K-like CHHC zinc finger

  2. NM_001439867.1 → NP_001426796.1  U11/U12 small nuclear ribonucleoprotein 48 kDa protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000017
    UniProtKB/TrEMBL
    A0ABK0M5K2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    26801818..26821605 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006253788.5 → XP_006253850.1  

    Related
    ENSRNOP00000110712.1, ENSRNOT00000145911.1
    Conserved Domains (1) summary
    pfam05253
    Location:57 → 79
    zf-U11-48K; U11-48K-like CHHC zinc finger

  2. XM_039095479.2 → XP_038951407.1  U11/U12 small nuclear ribonucleoprotein 48 kDa protein isoform X2

    UniProtKB/TrEMBL
    A0A8I6A3E2, A6J7A9, D3ZJA5
    Related
    ENSRNOP00000018508.6, ENSRNOT00000018508.8
    Conserved Domains (1) summary
    pfam05253
    Location:57 → 79
    zf-U11-48K; U11-48K-like CHHC zinc finger

  3. XM_006253787.5 → XP_006253849.1  

    Related
    ENSRNOP00000085198.1, ENSRNOT00000110730.2
    Conserved Domains (1) summary
    pfam05253
    Location:57 → 79
    zf-U11-48K; U11-48K-like CHHC zinc finger

  4. XM_063276160.1 → XP_063132230.1  U11/U12 small nuclear ribonucleoprotein 48 kDa protein isoform X4

Nucleotide Protein Strain
Heading Accession and Version

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