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CFAP20 cilia and flagella associated protein 20 [ Homo sapiens (human) ]

Gene ID: 29105, updated on 5-Jul-2020

Summary

Official Symbol
CFAP20provided by HGNC
Official Full Name
cilia and flagella associated protein 20provided by HGNC
Primary source
HGNC:HGNC:29523
See related
Ensembl:ENSG00000070761 MIM:617906
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GTL3; BUG22; EVORF; fSAP23; C16orf80
Expression
Ubiquitous expression in testis (RPKM 19.9), placenta (RPKM 16.9) and 25 other tissues See more
Orthologs

Genomic context

See CFAP20 in Genome Data Viewer
Location:
16q21
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (58113588..58129425, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (58147496..58163296, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene matrix metallopeptidase 15 Neighboring gene TIMELESS interacting protein pseudogene Neighboring gene uncharacterized LOC101927556 Neighboring gene casein kinase 2 alpha 2 Neighboring gene RNA, 7SL, cytoplasmic 645, pseudogene Neighboring gene coiled-coil domain containing 113

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cilium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
multicellular organism development TAS
Traceable Author Statement
more info
PubMed 
positive regulation of cell motility IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of cell motility IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of feeding behavior IDA
Inferred from Direct Assay
more info
PubMed 
protein polyglutamylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cilium beat frequency involved in ciliary motility IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of cilium beat frequency involved in ciliary motility IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
centriole IDA
Inferred from Direct Assay
more info
PubMed 
ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ciliary basal body IDA
Inferred from Direct Assay
more info
PubMed 
cilium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cilium IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
extracellular exosome HDA PubMed 
microtubule IEA
Inferred from Electronic Annotation
more info
 
motile cilium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
cilia- and flagella-associated protein 20
Names
UPF0468 protein C16orf80
basal body up-regulated protein 22
flagellar associated protein 20 homolog
functional spliceosome-associated protein 23
gene trap locus 3
transcription factor IIB

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013242.3NP_037374.1  cilia- and flagella-associated protein 20

    See identical proteins and their annotated locations for NP_037374.1

    Status: VALIDATED

    Source sequence(s)
    AV751497, BC005152
    Consensus CDS
    CCDS10793.1
    UniProtKB/Swiss-Prot
    Q9Y6A4
    Related
    ENSP00000262498.3, ENST00000262498.8
    Conserved Domains (1) summary
    pfam05018
    Location:6185
    DUF667; Protein of unknown function (DUF667)

RNA

  1. NR_136632.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC026771, AI379428, BU730963, CN364433, HY042096
    Related
    ENST00000562622.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    58113588..58129425 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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