Format

Send to:

Choose Destination

GTPBP8 GTP binding protein 8 (putative) [ Homo sapiens (human) ]

Gene ID: 29083, updated on 23-Nov-2021

Summary

Official Symbol
GTPBP8provided by HGNC
Official Full Name
GTP binding protein 8 (putative)provided by HGNC
Primary source
HGNC:HGNC:25007
See related
Ensembl:ENSG00000163607
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HSPC135
Expression
Ubiquitous expression in testis (RPKM 4.6), thyroid (RPKM 3.8) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See GTPBP8 in Genome Data Viewer
Location:
3q13.2
Exon count:
6
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (112990984..113001969)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (112709831..112720816)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene CD200R1L antisense RNA 1 Neighboring gene CD200 receptor 1 like Neighboring gene CD200 receptor 1 Neighboring gene NEPRO antisense RNA 1 Neighboring gene nucleolus and neural progenitor protein Neighboring gene VISTA enhancer hs1685

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014170.4NP_054889.2  GTP-binding protein 8 isoform 1

    See identical proteins and their annotated locations for NP_054889.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC074044, AF161484, AI367201, BC000003, CA429378
    Consensus CDS
    CCDS33820.1
    UniProtKB/Swiss-Prot
    Q8N3Z3
    UniProtKB/TrEMBL
    Q9P025
    Related
    ENSP00000373176.2, ENST00000383678.8
    Conserved Domains (1) summary
    cd01876
    Location:112280
    YihA_EngB; YihA (EngB) GTPase family
  2. NM_138485.2NP_612494.1  GTP-binding protein 8 isoform 2

    See identical proteins and their annotated locations for NP_612494.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1, resulting in an isoform (2) that is missing an internal segment compared to isoform 1.
    Source sequence(s)
    AC074044, AI367201, BI830308, BX354218, CA429378
    Consensus CDS
    CCDS33821.1
    UniProtKB/Swiss-Prot
    Q8N3Z3
    Related
    ENSP00000373175.3, ENST00000383677.7
    Conserved Domains (1) summary
    cd01876
    Location:113247
    YihA_EngB; YihA (EngB) GTPase family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    112990984..113001969
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001008235.1: Suppressed sequence

    Description
    NM_001008235.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
  2. NM_001008236.1: Suppressed sequence

    Description
    NM_001008236.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Support Center