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Trappc11 trafficking protein particle complex subunit 11 [ Rattus norvegicus (Norway rat) ]

Gene ID: 290746, updated on 3-Jun-2026
Official Symbol
Trappc11provided by RGD
Official Full Name
trafficking protein particle complex subunit 11provided by RGD
Primary source
RGD:1309765
See related
Ensembl:ENSRNOG00000022482 AllianceGenome:RGD:1309765
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309765
Summary
Predicted to be involved in several processes, including constitutive secretory pathway; endoplasmic reticulum to Golgi vesicle-mediated transport; and regulation of protein complex stability. Predicted to be located in Golgi apparatus. Predicted to be part of TRAPP complex. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2S. Orthologous to human TRAPPC11 (trafficking protein particle complex subunit 11). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Adrenal (RPKM 157.5), Kidney (RPKM 154.3) and 9 other tissues See more
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See Trappc11 in Genome Data Viewer
Location:
16q11
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (51465631..51512003)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (44733169..44779324)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (47874993..47920822)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene ERH, mRNA splicing and mitosis factor, pseudogene 2 Neighboring gene uncharacterized LOC134482503 Neighboring gene RWD domain containing 4 Neighboring gene uncharacterized LOC134482545 Neighboring gene uncharacterized LOC102551690 Neighboring gene small nucleolar RNA SNORA70

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Mutations in TRAPPC11 are associated with a congenital disorder of glycosylation. Matalonga L, et al. Hum Mutat, 2017 Feb. PMID 27862579
  2. C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking. Scrivens PJ, et al. Mol Biol Cell, 2011 Jun 15. PMID 21525244, Free PMC Article
  3. A genome-wide RNA interference screen identifies two novel components of the metazoan secretory pathway. Wendler F, et al. EMBO J, 2010 Jan 20. PMID 19942856, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in Golgi organization ISO
Inferred from Sequence Orthology
more info
  
involved_in constitutive secretory pathway ISO
Inferred from Sequence Orthology
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of protein complex stability ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
part_of TRAPP complex ISO
Inferred from Sequence Orthology
more info
  
Preferred Names
trafficking protein particle complex subunit 11
Names
trafficking protein particle complex 11

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001169115.1 → NP_001162586.1  trafficking protein particle complex subunit 11

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000016
    UniProtKB/TrEMBL
    A0A0G2K1K5, A6JPL4
    Conserved Domains (2) summary
    pfam11817
    Location:263 → 522
    Foie-gras_1; Foie gras liver health family 1
    pfam12742
    Location:1036 → 1095
    Gryzun-like; Gryzun, putative Golgi trafficking

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    51465631..51512003
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006253134.4 → XP_006253196.1  trafficking protein particle complex subunit 11 isoform X1

    See identical proteins and their annotated locations for XP_006253196.1

    UniProtKB/TrEMBL
    A6JPL4, D3ZHI8
    Conserved Domains (2) summary
    pfam11817
    Location:263 → 522
    Foie-gras_1; Foie gras liver health family 1
    pfam12742
    Location:1036 → 1095
    Gryzun-like; Gryzun, putative Golgi trafficking

  2. XM_063275230.1 → XP_063131300.1  trafficking protein particle complex subunit 11 isoform X2

    UniProtKB/TrEMBL
    A0A0G2K1K5, A6JPL4
    Related
    ENSRNOP00000071879.2, ENSRNOT00000079466.3

  3. XM_063275232.1 → XP_063131302.1  trafficking protein particle complex subunit 11 isoform X3

    UniProtKB/TrEMBL
    A6JPL4

  4. XM_006253135.4 → XP_006253197.1  trafficking protein particle complex subunit 11 isoform X1

    See identical proteins and their annotated locations for XP_006253197.1

    UniProtKB/TrEMBL
    A6JPL4, D3ZHI8
    Related
    ENSRNOP00000018969.6, ENSRNOT00000018969.9
    Conserved Domains (2) summary
    pfam11817
    Location:263 → 522
    Foie-gras_1; Foie gras liver health family 1
    pfam12742
    Location:1036 → 1095
    Gryzun-like; Gryzun, putative Golgi trafficking

  5. XM_063275231.1 → XP_063131301.1  trafficking protein particle complex subunit 11 isoform X2

    UniProtKB/TrEMBL
    A0A0G2K1K5, A6JPL4
Nucleotide Protein Strain
Heading Accession and Version

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