Format

Send to:

Choose Destination

MAGEH1 MAGE family member H1 [ Homo sapiens (human) ]

Gene ID: 28986, updated on 7-Jun-2020

Summary

Official Symbol
MAGEH1provided by HGNC
Official Full Name
MAGE family member H1provided by HGNC
Primary source
HGNC:HGNC:24092
See related
Ensembl:ENSG00000187601 MIM:300548
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
APR1; APR-1; MAGEH
Summary
This gene belongs to the non-CT (non cancer/testis) subgroup of the melanoma-associated antigen (MAGE) superfamily. The encoded protein is likely associated with apoptosis, cell cycle arrest, growth inhibition or cell differentiation. The protein may be involved in the atRA (all-trans retinoic acid) signaling through the STAT1-alpha (signal transducer and activator of transcription 1-alpha) pathway. [provided by RefSeq, Aug 2013]
Orthologs

Genomic context

See MAGEH1 in Genome Data Viewer
Location:
Xp11.21
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (55452127..55453566)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (55478538..55479999)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene PAGE family member 5 pseudogene Neighboring gene microRNA 4536-1 Neighboring gene microRNA 4536-2 Neighboring gene uncharacterized LOC101928692 Neighboring gene ubiquitin specific peptidase 51 Neighboring gene MAGE family member E1 pseudogene

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
apoptotic process TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
melanoma-associated antigen H1
Names
apoptosis-related protein 1
melanoma antigen family H, 1
melanoma antigen family H1
restin

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_013248.1 RefSeqGene

    Range
    5023..6462
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_014061.5NP_054780.2  melanoma-associated antigen H1

    See identical proteins and their annotated locations for NP_054780.2

    Status: REVIEWED

    Source sequence(s)
    AA634056, AF143235
    Consensus CDS
    CCDS14369.1
    UniProtKB/Swiss-Prot
    Q9H213
    Related
    ENSP00000343706.1, ENST00000342972.3
    Conserved Domains (1) summary
    pfam01454
    Location:62173
    MAGE; MAGE family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    55452127..55453566
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center