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SNX24 sorting nexin 24 [ Homo sapiens (human) ]

Gene ID: 28966, updated on 23-Nov-2021

Summary

Official Symbol
SNX24provided by HGNC
Official Full Name
sorting nexin 24provided by HGNC
Primary source
HGNC:HGNC:21533
See related
Ensembl:ENSG00000064652
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SBBI31; PRO1284
Expression
Ubiquitous expression in placenta (RPKM 4.0), thyroid (RPKM 3.8) and 25 other tissues See more
Orthologs
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Genomic context

See SNX24 in Genome Data Viewer
Location:
5q23.2
Exon count:
13
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (122845510..123029318)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (122181308..122344900)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2201 Neighboring gene arginine-fifty homeobox pseudogene 1 Neighboring gene uncharacterized LOC105379154 Neighboring gene sorting nexin 2 Neighboring gene RNA, 7SL, cytoplasmic 689, pseudogene Neighboring gene PPIC antisense RNA 1 Neighboring gene peptidylprolyl isomerase C Neighboring gene RNA, 7SL, cytoplasmic 711, pseudogene Neighboring gene PRDM6 antisense RNA 1 Neighboring gene PR/SET domain 6

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
Genome-wide meta-analysis identifies new susceptibility loci for migraine.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables phosphatidylinositol phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables phosphatidylinositol-3-phosphate binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidylinositol-4-phosphate binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidylinositol-5-phosphate binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasmic vesicle membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
sorting nexin-24
Names
sorting nexing 24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014035.4NP_054754.1  sorting nexin-24

    See identical proteins and their annotated locations for NP_054754.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript and encodes a protein.
    Source sequence(s)
    AF139461, BC010886, BQ278046, BU623609
    Consensus CDS
    CCDS4132.1
    UniProtKB/Swiss-Prot
    Q9Y343
    Related
    ENSP00000261369.4, ENST00000261369.9
    Conserved Domains (1) summary
    cd06880
    Location:1111
    PX_SNX22; The phosphoinositide binding Phox Homology domain of Sorting Nexin 22

RNA

  1. NR_146145.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AF139461, BC010886, BQ278046, BU623609, CN362247

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    122845510..123029318
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006714592.4XP_006714655.1  sorting nexin-24 isoform X4

    Conserved Domains (1) summary
    cd06880
    Location:1111
    PX_SNX22; The phosphoinositide binding Phox Homology domain of Sorting Nexin 22
  2. XM_017009395.1XP_016864884.1  sorting nexin-24 isoform X6

  3. XM_011543349.3XP_011541651.1  sorting nexin-24 isoform X1

    Conserved Domains (1) summary
    cd06880
    Location:1144
    PX_SNX22; The phosphoinositide binding Phox Homology domain of Sorting Nexin 22
  4. XM_011543350.3XP_011541652.1  sorting nexin-24 isoform X3

    Conserved Domains (1) summary
    cd06880
    Location:1144
    PX_SNX22; The phosphoinositide binding Phox Homology domain of Sorting Nexin 22
  5. XM_011543352.1XP_011541654.1  sorting nexin-24 isoform X7

    Conserved Domains (1) summary
    cl02563
    Location:1117
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
  6. XM_017009396.1XP_016864885.1  sorting nexin-24 isoform X7

    Conserved Domains (1) summary
    cl02563
    Location:1117
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
  7. XM_005271972.5XP_005272029.1  sorting nexin-24 isoform X2

    Conserved Domains (1) summary
    cd06880
    Location:1111
    PX_SNX22; The phosphoinositide binding Phox Homology domain of Sorting Nexin 22
  8. XM_017009394.1XP_016864883.1  sorting nexin-24 isoform X5

    Conserved Domains (1) summary
    cl02563
    Location:184
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

RNA

  1. XR_001742058.1 RNA Sequence

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