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THI6 bifunctional hydroxyethylthiazole kinase/thiamine-phosphate diphosphorylase [ Nakaseomyces glabratus ]

Gene ID: 2887447, updated on 16-Jul-2025
Gene symbol
THI6
Gene description
bifunctional hydroxyethylthiazole kinase/thiamine-phosphate diphosphorylase
Locus tag
GVI51_E05533
See related
FungiDB:GVI51_E05533; VEuPathDB:GVI51_E05533
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Nakaseomyces glabratus (strain: ATCC 2001, nat-host: Homo sapiens, culture-collection: ATCC:2001, type-material: type material of Cryptococcus glabratus)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Nakaseomyces
Orthologs
all
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See THI6 in Genome Data Viewer
Location:
chromosome: E
Exon count:
1
Sequence:
Chromosome: E; NC_088955.1 (594209..595831)

Chromosome E - NC_088955.1Genomic Context describing neighboring genes Neighboring gene pseudouridine synthase PUS1 Neighboring gene U2 snRNP complex subunit LEA1 Neighboring gene Cbp3p Neighboring gene GTPase BMS1

Genomic Sequence:
NC_088955.1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. De novo genome assembly of Candida glabrata reveals cell wall protein complement and structure of dispersed tandem repeat arrays. Xu Z, et al. Mol Microbiol, 2020 Jun. PMID 32068314
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

  • CAGL0E05808g
    Bifunctional enzyme of thiamine biosynthesis, with thiamine-phosphate pyrophosphorylase and 4-methyl-5-beta-hydroxyethylthiazole kinase activities; active as a homohexamer

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hydroxyethylthiazole kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables thiamine-phosphate diphosphorylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in thiamine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
bifunctional hydroxyethylthiazole kinase/thiamine-phosphate diphosphorylase
XP_445941.1
  • CAGL0E05808g
    Bifunctional enzyme of thiamine biosynthesis, with thiamine-phosphate pyrophosphorylase and 4-methyl-5-beta-hydroxyethylthiazole kinase activities; active as a homohexamer

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_088955.1 Reference assembly

    Range
    594209..595831
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_445941.1 → XP_445941.1  bifunctional hydroxyethylthiazole kinase/thiamine-phosphate diphosphorylase

    See identical proteins and their annotated locations for XP_445941.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0W0CWP0, Q6FV03
    Conserved Domains (2) summary
    PRK00043
    Location:8 → 232
    thiE; thiamine phosphate synthase
    cl00192
    Location:264 → 530
    ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...
Nucleotide Protein
Heading Accession and Version

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