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Mospd3 motile sperm domain containing 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 288557, updated on 5-Sep-2025
Official Symbol
Mospd3provided by RGD
Official Full Name
motile sperm domain containing 3provided by RGD
Primary source
RGD:1304973
See related
Ensembl:ENSRNOG00000001396 AllianceGenome:RGD:1304973
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to act upstream of or within heart development. Predicted to be located in membrane. Orthologous to human MOSPD3 (motile sperm domain containing 3). [provided by Alliance of Genome Resources, Apr 2025]
Expression
Biased expression in Liver (RPKM 81.4), Thymus (RPKM 78.6) and 9 other tissues See more
Orthologs
human mouse all
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See Mospd3 in Genome Data Viewer
Location:
12q12
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (24728012..24737078)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (19095203..19100303)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (22164978..22169251)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene F-box protein 24 Neighboring gene procollagen C-endopeptidase enhancer Neighboring gene transferrin receptor 2 Neighboring gene actin-like 6B

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Hypersensitivity to pentylenetetrazol-induced convulsion in mice lacking the PLC-related inactive protein-1. Yamaguchi T, et al. Brain Res, 2004 Oct 29. PMID 15464766
  2. A novel transmembrane MSP-containing protein that plays a role in right ventricle development. Pall GS, et al. Genomics, 2004 Dec. PMID 15533722
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Clone Names

  • MGC116409

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within heart development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within heart development ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
motile sperm domain-containing protein 3

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025629.1 → NP_001020800.1  motile sperm domain-containing protein 3

    See identical proteins and their annotated locations for NP_001020800.1

    Status: PROVISIONAL

    Source sequence(s)
    BC099230
    UniProtKB/TrEMBL
    A6J017, F7F0P6, Q4KLG1
    Conserved Domains (1) summary
    pfam00635
    Location:41 → 133
    Motile_Sperm; MSP (Major sperm protein) domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    24728012..24737078
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039089204.2 → XP_038945132.1  motile sperm domain-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    A6J014
    Conserved Domains (1) summary
    pfam00635
    Location:41 → 133
    Motile_Sperm; MSP (Major sperm protein) domain

  2. XM_006249115.5 → XP_006249177.1  motile sperm domain-containing protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006249177.1

    UniProtKB/TrEMBL
    A6J017, F7F0P6, Q4KLG1
    Related
    ENSRNOP00000001890.4, ENSRNOT00000001890.9
    Conserved Domains (1) summary
    pfam00635
    Location:41 → 133
    Motile_Sperm; MSP (Major sperm protein) domain
Nucleotide Protein Strain
Heading Accession and Version

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