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Spnl1 sialophorin like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 288521, updated on 29-Feb-2024

Summary

Official Symbol
Spnl1provided by RGD
Official Full Name
sialophorin like 1provided by RGD
Primary source
RGD:1359506
See related
Ensembl:ENSRNOG00000028414 AllianceGenome:RGD:1359506
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable heat shock protein binding activity. Predicted to be involved in cell surface receptor signaling pathway; defense response to bacterium; and regulation of immune response. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Orthologous to human SPN (sialophorin). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 176.9) See more
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Genomic context

Location:
12q11
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (21250354..21261494, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (16136583..16147719, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (18291901..18303041, complement)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene sialophorin like 2 Neighboring gene sialophorin, pseudogene 8 Neighboring gene sialophorin, pseudogene 5 Neighboring gene sialophorin, pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables heat shock protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in defense response to bacterium IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of T cell activation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of T cell migration IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
sialophorin like 1
Names
Leukosialin-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013868.1NP_001013890.1  sialophorin like 1 precursor

    See identical proteins and their annotated locations for NP_001013890.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079301
    UniProtKB/TrEMBL
    Q6AXV5
    Related
    ENSRNOP00000032358.3, ENSRNOT00000032844.5

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    21250354..21261494 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)