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IGLV2-14 immunoglobulin lambda variable 2-14 [ Homo sapiens (human) ]

Gene ID: 28815, updated on 10-Dec-2024

Summary

Official Symbol
IGLV2-14provided by HGNC
Official Full Name
immunoglobulin lambda variable 2-14provided by HGNC
Primary source
HGNC:HGNC:5888
See related
Ensembl:ENSG00000211666 IMGT/GENE-DB:IGLV2-14; AllianceGenome:HGNC:5888
Gene type
other
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
V1-4; IGLV214
Summary
Predicted to be involved in immune response. Located in extracellular exosome. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See IGLV2-14 in Genome Data Viewer
Location:
22q11.22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (22758741..22759211)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (23181714..23182184)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (23101230..23101700)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene immunoglobulin lambda locus Neighboring gene ReSE screen-validated silencer GRCh37_chr22:23112882-23113048 Neighboring gene immunoglobulin lambda variable 3-16 Neighboring gene immunoglobulin lambda variable 3-15 (pseudogene) Neighboring gene immunoglobulin lambda variable 3-13 (pseudogene) Neighboring gene immunoglobulin lambda variable 3-12

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Other Names

  • Ig lambda chain V-II region TOG

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables antigen binding NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
involved_in adaptive immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in immune response NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular exosome HDA PubMed 
located_in extracellular region NAS
Non-traceable Author Statement
more info
PubMed 
located_in extracellular region TAS
Traceable Author Statement
more info
 
part_of immunoglobulin complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_000002.1 

    Range
    725214..725684
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    22758741..22759211
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    23181714..23182184
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)