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Cdc45 cell division cycle 45 [ Rattus norvegicus (Norway rat) ]

Gene ID: 287961, updated on 22-Nov-2020

Summary

Official Symbol
Cdc45provided by RGD
Official Full Name
cell division cycle 45provided by RGD
Primary source
RGD:1590928
See related
Ensembl:ENSRNOG00000050071
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Cdc45l
Expression
Biased expression in Thymus (RPKM 75.7), Spleen (RPKM 37.8) and 8 other tissues See more
Orthologs

Genomic context

See Cdc45 in Genome Data Viewer
Location:
11q23
Exon count:
20
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (86328785..86354099)
106 current Rn_Celera (GCF_000002265.2) 11 AC_000079.1 (80966334..80990943)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 11 NC_005110.3 (89431161..89456065)

Chromosome 11 - NC_005110.4Genomic Context describing neighboring genes Neighboring gene similar to CG15908-PA Neighboring gene ubiquitin recognition factor in ER associated degradation 1 Neighboring gene claudin 5 Neighboring gene serine/threonine-protein phosphatase 2A catalytic subunit alpha-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
DNA replication origin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
single-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
DNA replication initiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell division IEA
Inferred from Electronic Annotation
more info
 
double-strand break repair via break-induced replication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitotic DNA replication preinitiation complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of chromatin silencing at telomere IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
DNA replication preinitiation complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
centrosome IEA
Inferred from Electronic Annotation
more info
 
centrosome ISO
Inferred from Sequence Orthology
more info
 
ciliary basal body ISO
Inferred from Sequence Orthology
more info
 
nuclear pre-replicative complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
cell division control protein 45 homolog
Names
CDC45 cell division cycle 45-like
CDC45-related protein
cell division cycle 45 homolog

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105866.2NP_001099336.1  cell division control protein 45 homolog

    See identical proteins and their annotated locations for NP_001099336.1

    Status: PROVISIONAL

    Source sequence(s)
    BC161946
    UniProtKB/TrEMBL
    B1WBZ4
    Related
    ENSRNOP00000066206.1, ENSRNOT00000072027.2
    Conserved Domains (1) summary
    pfam02724
    Location:19565
    CDC45; CDC45-like protein

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005110.4 Reference Rnor_6.0 Primary Assembly

    Range
    86328785..86354099
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008768866.2XP_008767088.1  cell division control protein 45 homolog isoform X1

    See identical proteins and their annotated locations for XP_008767088.1

    UniProtKB/TrEMBL
    B1WBZ4
    Conserved Domains (1) summary
    pfam02724
    Location:19565
    CDC45; CDC45-like protein

Alternate Rn_Celera

Genomic

  1. AC_000079.1 Alternate Rn_Celera

    Range
    80966334..80990943
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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