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Cep112 centrosomal protein 112 [ Rattus norvegicus (Norway rat) ]

Gene ID: 287776, updated on 18-Apr-2019

Summary

Official Symbol
Cep112provided by RGD
Official Full Name
centrosomal protein 112provided by RGD
Primary source
RGD:1564168
See related
Ensembl:ENSRNOG00000024557
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ccdc46; RGD1564168
Annotation information
Annotation category: partial on reference assembly
Expression
Biased expression in Testes (RPKM 48.1), Lung (RPKM 28.8) and 9 other tissues See more
Orthologs

Genomic context

See Cep112 in Genome Data Viewer
Location:
10q32.1
Exon count:
28
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (96660294..97146426)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (96387815..96868508)

Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene protein kinase C, alpha Neighboring gene transfer RNA alanine (anticodon AGC) Neighboring gene apolipoprotein H Neighboring gene uncharacterized LOC108352152 Neighboring gene uncharacterized LOC108352227 Neighboring gene axin 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
receptor localization to synapse IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
centrosome IEA
Inferred from Electronic Annotation
more info
 
centrosome ISO
Inferred from Sequence Orthology
more info
PubMed 
inhibitory synapse IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
centrosomal protein of 112 kDa
Names
centrosomal protein 112kDa
coiled-coil domain containing 46
coiled-coil domain-containing protein 46

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105849.1NP_001099319.1  centrosomal protein of 112 kDa

    See identical proteins and their annotated locations for NP_001099319.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473948
    Related
    ENSRNOP00000038168.6, ENSRNOT00000037067.6
    Conserved Domains (3) summary
    COG0419
    Location:430997
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam14846
    Location:65150
    DUF4485; Domain of unknown function (DUF4485)
    cl00459
    Location:9091006
    MIT_CorA-like; metal ion transporter CorA-like divalent cation transporter superfamily

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

    Range
    96660294..97146426
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017597147.1XP_017452636.1  centrosomal protein of 112 kDa isoform X1

    Conserved Domains (3) summary
    COG0419
    Location:430997
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam14846
    Location:65150
    DUF4485; Domain of unknown function (DUF4485)
    cl00459
    Location:9091006
    MIT_CorA-like; metal ion transporter CorA-like divalent cation transporter superfamily

Alternate Rn_Celera

Genomic

  1. AC_000078.1 Alternate Rn_Celera

    Range
    92030774..92496883
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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