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Fut11 fucosyltransferase 11 [ Rattus norvegicus (Norway rat) ]

Gene ID: 286971, updated on 5-Sep-2025
Official Symbol
Fut11provided by RGD
Official Full Name
fucosyltransferase 11provided by RGD
Primary source
RGD:628731
See related
Ensembl:ENSRNOG00000009274 AllianceGenome:RGD:628731
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in N-glycan fucosylation. Predicted to be located in Golgi cisterna membrane and Golgi membrane. Human ortholog(s) of this gene implicated in stomach cancer. Orthologous to human FUT11 (fucosyltransferase 11). [provided by Alliance of Genome Resources, Apr 2025]
Expression
Biased expression in Lung (RPKM 69.0), Adrenal (RPKM 65.6) and 9 other tissues See more
Orthologs
human mouse all
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Location:
15p16
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (3648022..3651582, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (3598768..3602328, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (4031504..4035064, complement)

Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 1 Neighboring gene SEC24 homolog C, COPII coat complex component Neighboring gene small nucleolar RNA SNORA51

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Knockdown of FUT11 inhibits the progression of gastric cancer via the PI3K/AKT pathway. Cao W, et al. Heliyon, 2023 Jul. PMID 37483811, Free PMC Article
  2. Activity, splice variants, conserved peptide motifs, and phylogeny of two new alpha1,3-fucosyltransferase families (FUT10 and FUT11). Mollicone R, et al. J Biol Chem, 2009 Feb 13. PMID 19088067
  3. Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism. Roos C, et al. J Biol Chem, 2002 Feb 1. PMID 11698403
  4. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Markers

Homology

Clone Names

  • MGC94472

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables alpha-(1->3)-fucosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alpha-(1->3)-fucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables fucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables fucosyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables fucosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptide-O-fucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptide-O-fucosyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables peptide-O-fucosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in N-glycan fucosylation IEA
Inferred from Electronic Annotation
more info
  
involved_in N-glycan fucosylation ISO
Inferred from Sequence Orthology
more info
  
involved_in N-glycan processing ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in fucosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of protein secretion IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of protein secretion ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of protein secretion ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in protein O-linked glycosylation via fucose IEA
Inferred from Electronic Annotation
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
is_active_in endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
GDP-fucose protein O-fucosyltransferase 4
Names
alpha-(1,3)-fucosyltransferase 11
alpha3-fucosyltransferase 11
fuc-TXI
fucT-XI
fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
fucosyltransferase XI
galactoside 3-L-fucosyltransferase 11
NP_775430.2

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173308.2 → NP_775430.2  GDP-fucose protein O-fucosyltransferase 4 precursor

    See identical proteins and their annotated locations for NP_775430.2

    Status: PROVISIONAL

    Source sequence(s)
    BC079316
    UniProtKB/Swiss-Prot
    Q68FV3, Q8CG40
    UniProtKB/TrEMBL
    A6KKP8
    Related
    ENSRNOP00000012300.1, ENSRNOT00000012300.5
    Conserved Domains (2) summary
    pfam00852
    Location:217 → 356
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:120 → 181
    Glyco_tran_10_N; Fucosyltransferase, N-terminal

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086033.1 Reference GRCr8

    Range
    3648022..3651582 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q68FV3.1 GenPept UniProtKB/Swiss-Prot:Q68FV3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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