U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Kif19a kinesin family member 19A [ Mus musculus (house mouse) ]

Gene ID: 286942, updated on 21-Apr-2024

Summary

Official Symbol
Kif19aprovided by MGI
Official Full Name
kinesin family member 19Aprovided by MGI
Primary source
MGI:MGI:2447024
See related
Ensembl:ENSMUSG00000010021 AllianceGenome:MGI:2447024
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Kif19
Summary
Enables plus-end-directed microtubule motor activity. Involved in axonemal microtubule depolymerization and plus-end specific microtubule depolymerization. Located in cilium. Orthologous to human KIF19 (kinesin family member 19). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in ovary adult (RPKM 6.6), testis adult (RPKM 4.2) and 11 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
11 E2; 11 80.44 cM
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (114656227..114681565)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (114764970..114791166)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene tweety family member 2 Neighboring gene dynein axonemal intermediate chain 2 Neighboring gene STARR-positive B cell enhancer mm9_chr11:114606533-114606834 Neighboring gene BTB domain containing 17 Neighboring gene G protein-coupled receptor 142 Neighboring gene G protein-coupled receptor, family C, group 5, member C

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables microtubule motor activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables plus-end-directed microtubule motor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables plus-end-directed microtubule motor activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in axonemal microtubule depolymerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in microtubule-based movement IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in plus-end specific microtubule depolymerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cilium IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
part_of kinesin complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in microtubule IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
kinesin-like protein KIF19
Names
KIF19A-like protein
N-8 kinesin
oocyte-G1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001102615.2NP_001096085.1  kinesin-like protein KIF19

    See identical proteins and their annotated locations for NP_001096085.1

    Status: VALIDATED

    Source sequence(s)
    AL663079
    Consensus CDS
    CCDS36367.1
    UniProtKB/Swiss-Prot
    A7DTH0, Q99PT9
    UniProtKB/TrEMBL
    A9XMT8
    Related
    ENSMUSP00000081398.6, ENSMUST00000084368.12
    Conserved Domains (2) summary
    smart00129
    Location:14353
    KISc; Kinesin motor, catalytic domain. ATPase
    cd01370
    Location:11346
    KISc_KIP3_like; Kinesin motor domain, KIP3-like subgroup

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    114656227..114681565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)