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PRDX2 peroxiredoxin 2 [ Bos taurus (cattle) ]

Gene ID: 286793, updated on 3-Feb-2019

Summary

Official Symbol
PRDX2provided by VGNC
Official Full Name
peroxiredoxin 2provided by VGNC
Primary source
VGNC:VGNC:33300
See related
BGD:BT10759; Ensembl:ENSBTAG00000012062
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs

Genomic context

See PRDX2 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 7 NC_037334.1 (12730328..12733442)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 7 AC_000164.1 (13844492..13848481)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene retbindin Neighboring gene ribonuclease H2 subunit A Neighboring gene JunB proto-oncogene, AP-1 transcription factor subunit Neighboring gene hook microtubule tethering protein 2

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
T cell proliferation IEA
Inferred from Electronic Annotation
more info
 
activation of MAPK activity IEA
Inferred from Electronic Annotation
more info
 
homeostasis of number of cells IEA
Inferred from Electronic Annotation
more info
 
negative regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
negative regulation of T cell differentiation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IEA
Inferred from Electronic Annotation
more info
 
negative regulation of lipopolysaccharide-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
negative regulation of reactive oxygen species metabolic process IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of blood coagulation IEA
Inferred from Electronic Annotation
more info
 
regulation of hydrogen peroxide metabolic process IEA
Inferred from Electronic Annotation
more info
 
respiratory burst involved in inflammatory response IEA
Inferred from Electronic Annotation
more info
 
response to lipopolysaccharide IEA
Inferred from Electronic Annotation
more info
 
thymus development IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
peroxiredoxin-2
NP_777188.1
XP_005208710.1
XP_010805021.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174763.2NP_777188.1  peroxiredoxin-2

    See identical proteins and their annotated locations for NP_777188.1

    Status: PROVISIONAL

    Source sequence(s)
    AF305562
    UniProtKB/Swiss-Prot
    Q9BGI3
    Related
    ENSBTAP00000015996.1, ENSBTAT00000015996.2
    Conserved Domains (1) summary
    cd03015
    Location:9180
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    12730328..12733442
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005208653.2XP_005208710.1  peroxiredoxin-2 isoform X1

    See identical proteins and their annotated locations for XP_005208710.1

    UniProtKB/Swiss-Prot
    Q9BGI3
    Conserved Domains (1) summary
    cd03015
    Location:9180
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...
  2. XM_010806719.3XP_010805021.1  peroxiredoxin-2 isoform X1

    See identical proteins and their annotated locations for XP_010805021.1

    UniProtKB/Swiss-Prot
    Q9BGI3
    Conserved Domains (1) summary
    cd03015
    Location:9180
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...
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