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GPR42 G protein-coupled receptor 42 [ Homo sapiens (human) ]

Gene ID: 2866, updated on 26-Oct-2022

Summary

Official Symbol
GPR42provided by HGNC
Official Full Name
G protein-coupled receptor 42provided by HGNC
Primary source
HGNC:HGNC:4500
See related
Ensembl:ENSG00000126251 MIM:603822; AllianceGenome:HGNC:4500
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FFAR1L; FFAR3L; GPR41L; GPR42P
Summary
Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See GPR42 in Genome Data Viewer
Location:
19q13.12
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (35371068..35372962)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (37915808..37917703)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (35861970..35863864)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene free fatty acid receptor 1 Neighboring gene free fatty acid receptor 3 Neighboring gene CRISPRi-validated cis-regulatory element chr19.3689 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene 7

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
G-protein coupled receptor 42
Names
G protein-coupled receptor 42 pseudogene
G-protein coupled receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001348195.2NP_001335124.1  G-protein coupled receptor 42

    Status: VALIDATED

    Source sequence(s)
    AC002511
    Consensus CDS
    CCDS12460.1
    UniProtKB/Swiss-Prot
    O15529
    UniProtKB/TrEMBL
    A0A0K0PUY3
    Related
    ENSP00000410925.1, ENST00000454971.3
    Conserved Domains (1) summary
    cd15170
    Location:15289
    7tmA_FFAR2_FFAR3; free fatty acid receptors 2, 3, and similar proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    35371068..35372962
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    37915808..37917703
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_008348.3: Suppressed sequence

    Description
    NG_008348.3: This RefSeq was removed because it is now thought that this gene does encode a protein.
  2. NM_005305.1: Suppressed sequence

    Description
    NM_005305.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.