Format

Send to:

Choose Destination

FFAR3 free fatty acid receptor 3 [ Homo sapiens (human) ]

Gene ID: 2865, updated on 23-Nov-2021

Summary

Official Symbol
FFAR3provided by HGNC
Official Full Name
free fatty acid receptor 3provided by HGNC
Primary source
HGNC:HGNC:4499
See related
Ensembl:ENSG00000185897 MIM:603821
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FFA3R; GPR41; GPR42
Expression
Biased expression in appendix (RPKM 1.2), fat (RPKM 0.6) and 13 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See FFAR3 in Genome Data Viewer
Location:
19q13.12
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (35358106..35360491)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (35849362..35851391)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene CD22 molecule Neighboring gene microRNA 5196 Neighboring gene free fatty acid receptor 1 Neighboring gene G protein-coupled receptor 42 Neighboring gene CRISPRi-validated cis-regulatory element chr19.3689

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to fatty acid IDA
Inferred from Direct Assay
more info
PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 
involved_in mucosal immune response ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of blood pressure ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of acute inflammatory response to non-antigenic stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of chemokine production ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of cytokine production involved in immune response ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of hormone biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of insulin receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of norepinephrine secretion ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of peptide hormone secretion ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in integral component of plasma membrane TAS
Traceable Author Statement
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
free fatty acid receptor 3
Names
G-protein coupled receptor 41

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_005304.5NP_005295.1  free fatty acid receptor 3

    See identical proteins and their annotated locations for NP_005295.1

    Status: VALIDATED

    Source sequence(s)
    AC002511, BC035657, DR004234
    Consensus CDS
    CCDS12459.1
    UniProtKB/Swiss-Prot
    O14843
    UniProtKB/TrEMBL
    A0A0K0PUW7
    Related
    ENSP00000328230.3, ENST00000327809.5
    Conserved Domains (1) summary
    cd15170
    Location:15289
    7tmA_FFAR2_FFAR3; free fatty acid receptors 2, 3, and similar proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    35358106..35360491
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011526858.2XP_011525160.1  free fatty acid receptor 3 isoform X1

    Conserved Domains (1) summary
    pfam00001
    Location:69313
    7tm_1; 7 transmembrane receptor (rhodopsin family)
Support Center