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YIPF6 Yip1 domain family member 6 [ Homo sapiens (human) ]

Gene ID: 286451, updated on 22-Sep-2022

Summary

Official Symbol
YIPF6provided by HGNC
Official Full Name
Yip1 domain family member 6provided by HGNC
Primary source
HGNC:HGNC:28304
See related
Ensembl:ENSG00000181704 MIM:300996; AllianceGenome:HGNC:28304
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FinGER6
Summary
Predicted to enable identical protein binding activity. Predicted to act upstream of or within intestinal epithelial cell development. Located in Golgi apparatus subcompartment and endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thyroid (RPKM 11.2), prostate (RPKM 8.9) and 25 other tissues See more
Orthologs
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Genomic context

See YIPF6 in Genome Data Viewer
Location:
Xq12-q13.1
Exon count:
7
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (68499051..68537282)
110 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (66932508..66970741)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (67718893..67757124)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene oligophrenin 1 Neighboring gene akirin 1 pseudogene 2 Neighboring gene nuclear distribution protein nudE-like 1-like Neighboring gene Sharpr-MPRA regulatory region 12156 Neighboring gene RNA, U6 small nuclear 245, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC21416

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
involved_in intestinal epithelial cell development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in COPII-coated ER to Golgi transport vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi medial cisterna IDA
Inferred from Direct Assay
more info
PubMed 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi trans cisterna IDA
Inferred from Direct Assay
more info
PubMed 
located_in cis-Golgi network IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in trans-Golgi network IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
protein YIPF6
Names
YIP1 family member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195214.2NP_001182143.1  protein YIPF6 isoform B

    See identical proteins and their annotated locations for NP_001182143.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (B) lacks an in-frame exon in the 5' coding region, compared to variant A. The resulting protein (isoform B) is shorter than isoform A.
    Source sequence(s)
    AK303992, AL928603, CN311465
    Consensus CDS
    CCDS56604.1
    UniProtKB/Swiss-Prot
    Q96EC8
    Related
    ENSP00000363751.2, ENST00000374622.3
    Conserved Domains (1) summary
    cl21557
    Location:22188
    Yip1; Yip1 domain
  2. NM_173834.4NP_776195.2  protein YIPF6 isoform A

    See identical proteins and their annotated locations for NP_776195.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (A) represents the longer transcript and encodes the longer isoform (A).
    Source sequence(s)
    AL928603, BC012469
    Consensus CDS
    CCDS14389.1
    UniProtKB/Swiss-Prot
    Q5JP08, Q96EC8
    Related
    ENSP00000417573.1, ENST00000462683.6
    Conserved Domains (1) summary
    cl21557
    Location:54231
    Yip1; Yip1 domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    68499051..68537282
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    66932508..66970741
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)