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ATP11C ATPase phospholipid transporting 11C [ Homo sapiens (human) ]

Gene ID: 286410, updated on 1-Jun-2020

Summary

Official Symbol
ATP11Cprovided by HGNC
Official Full Name
ATPase phospholipid transporting 11Cprovided by HGNC
Primary source
HGNC:HGNC:13554
See related
Ensembl:ENSG00000101974 MIM:300516
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ATPIG; ATPIQ; HACXL
Expression
Ubiquitous expression in liver (RPKM 9.4), urinary bladder (RPKM 5.9) and 24 other tissues See more
Orthologs

Genomic context

See ATP11C in Genome Data Viewer
Location:
Xq27.1
Exon count:
35
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (139726346..139933083, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (138808505..139015190, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene MCF.2 cell line derived transforming sequence Neighboring gene brain cytoplasmic RNA 1, pseudogene 1 Neighboring gene RNA, U6atac small nuclear 23, pseudogene Neighboring gene microRNA 505 Neighboring gene chromosome X open reading frame 66 Neighboring gene uncharacterized LOC728660

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
ion transmembrane transport TAS
Traceable Author Statement
more info
 
phospholipid translocation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phospholipid translocation NAS
Non-traceable Author Statement
more info
PubMed 
positive regulation of B cell differentiation IEA
Inferred from Electronic Annotation
more info
 
pre-B cell differentiation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
lysosomal membrane HDA PubMed 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 
recycling endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
phospholipid-transporting ATPase IG
Names
ATPase, class VI, type 11C
P4-ATPase flippase complex alpha subunit ATP11C
probable phospholipid-transporting ATPase IG
NP_001010986.2
NP_001340739.2
NP_001340740.2
NP_001340741.2
NP_775965.3
XP_016884928.1
XP_016884929.1
XP_016884930.1
XP_016884931.1
XP_016884932.1
XP_016884934.1
XP_016884935.1
XP_016884937.1
XP_016884938.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016550.2 RefSeqGene

    Range
    105796..211738
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001010986.3NP_001010986.2  phospholipid-transporting ATPase IG isoform b

    Status: VALIDATED

    Source sequence(s)
    AL161777, AL356785
    Consensus CDS
    CCDS35410.1
    Related
    ENSP00000355165.2, ENST00000361648.6
  2. NM_001353810.2NP_001340739.2  phospholipid-transporting ATPase IG isoform c

    Status: VALIDATED

    Source sequence(s)
    AL161777, AL356785, AL590077
    Related
    ENSP00000359588.1, ENST00000370557.5
  3. NM_001353811.2NP_001340740.2  phospholipid-transporting ATPase IG isoform d

    Status: VALIDATED

    Source sequence(s)
    AL161777, AL356785, AL590077
  4. NM_001353812.2NP_001340741.2  phospholipid-transporting ATPase IG isoform e

    Status: VALIDATED

    Source sequence(s)
    AL161777, AL356785, AL590077
  5. NM_173694.5NP_775965.3  phospholipid-transporting ATPase IG isoform a

    Status: VALIDATED

    Source sequence(s)
    AL161777, AL356785
    Consensus CDS
    CCDS14668.1
    Related
    ENSP00000332756.3, ENST00000327569.7

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    139726346..139933083 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017029449.1XP_016884938.1  phospholipid-transporting ATPase IG isoform X8

    Conserved Domains (4) summary
    pfam13246
    Location:203307
    Cation_ATPase; Cation transport ATPase (P-type)
    pfam16212
    Location:597824
    PhoLip_ATPase_C; Phospholipid-translocating P-type ATPase C-terminal
    cl14615
    Location:333409
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
    cl21460
    Location:546575
    HAD_like; Haloacid Dehalogenase-like Hydrolases
  2. XM_017029448.1XP_016884937.1  phospholipid-transporting ATPase IG isoform X7

  3. XM_017029440.2XP_016884929.1  phospholipid-transporting ATPase IG isoform X2

  4. XM_017029441.1XP_016884930.1  phospholipid-transporting ATPase IG isoform X2

  5. XM_017029442.1XP_016884931.1  phospholipid-transporting ATPase IG isoform X3

  6. XM_017029446.2XP_016884935.1  phospholipid-transporting ATPase IG isoform X6

  7. XM_017029439.2XP_016884928.1  phospholipid-transporting ATPase IG isoform X1

  8. XM_017029443.2XP_016884932.1  phospholipid-transporting ATPase IG isoform X4

  9. XM_017029445.2XP_016884934.1  phospholipid-transporting ATPase IG isoform X5

RNA

  1. XR_001755684.2 RNA Sequence

  2. XR_001755685.1 RNA Sequence

  3. XR_002958774.1 RNA Sequence

  4. XR_001755683.2 RNA Sequence

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