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LURAP1L leucine rich adaptor protein 1 like [ Homo sapiens (human) ]

Gene ID: 286343, updated on 5-Aug-2022

Summary

Official Symbol
LURAP1Lprovided by HGNC
Official Full Name
leucine rich adaptor protein 1 likeprovided by HGNC
Primary source
HGNC:HGNC:31452
See related
Ensembl:ENSG00000153714 MIM:616130; AllianceGenome:HGNC:31452
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LRAP35b; bA3L8.2; C9orf150; HYST0841
Summary
Predicted to be involved in positive regulation of I-kappaB kinase/NF-kappaB signaling. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta (RPKM 9.1), lung (RPKM 7.8) and 23 other tissues See more
Orthologs
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Genomic context

See LURAP1L in Genome Data Viewer
Location:
9p23
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (12775020..12823060)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (12784296..12832387)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (12775019..12823059)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene LURAP1L antisense RNA 1 Neighboring gene tyrosinase related protein 1 Neighboring gene RNA, 7SL, cytoplasmic 849, pseudogene Neighboring gene small nucleolar RNA, C/D box 137 Neighboring gene peroxiredoxin 1 pseudogene 1 Neighboring gene lupus La protein-like

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ38505, FLJ90271, MGC46502

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
leucine rich adaptor protein 1-like
Names
leucine repeat adaptor protein 35b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_203403.2NP_981948.1  leucine rich adaptor protein 1-like

    Status: VALIDATED

    Source sequence(s)
    AK095824, BC036923, BE464662, BM739457, BX508229, CD678148
    Consensus CDS
    CCDS6473.1
    UniProtKB/Swiss-Prot
    Q8IV03, Q8NCG2
    Related
    ENSP00000321026.3, ENST00000319264.4
    Conserved Domains (1) summary
    pfam14854
    Location:83193
    LURAP; Leucine rich adaptor protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    12775020..12823060
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005251443.4XP_005251500.1  leucine rich adaptor protein 1-like isoform X1

    Conserved Domains (1) summary
    pfam14854
    Location:83105
    LURAP; Leucine rich adaptor protein

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    12784296..12832387
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)