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DPY19L4 dpy-19 like 4 [ Homo sapiens (human) ]

Gene ID: 286148, updated on 1-Aug-2020

Summary

Official Symbol
DPY19L4provided by HGNC
Official Full Name
dpy-19 like 4provided by HGNC
Primary source
HGNC:HGNC:27829
See related
Ensembl:ENSG00000156162 MIM:613895
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in thyroid (RPKM 10.0), ovary (RPKM 7.2) and 25 other tissues See more
Orthologs

Genomic context

See DPY19L4 in Genome Data Viewer
Location:
8q22.1
Exon count:
20
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (94719708..94793836)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (95732103..95806076)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100288748 Neighboring gene epithelial splicing regulatory protein 1 Neighboring gene ribosomal protein S15a pseudogene 26 Neighboring gene integrator complex subunit 8 Neighboring gene ribosomal protein L17 pseudogene Neighboring gene cyclin E2 Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 6 Neighboring gene tumor protein p53 inducible nuclear protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC131885

Gene Ontology Provided by GOA

Function Evidence Code Pubs
mannosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
nuclear inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
probable C-mannosyltransferase DPY19L4
Names
dpy-19-like protein 4
protein dpy-19 homolog 4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_181787.3NP_861452.2  probable C-mannosyltransferase DPY19L4

    See identical proteins and their annotated locations for NP_861452.2

    Status: VALIDATED

    Source sequence(s)
    AP003692, BC110870, BP873374
    Consensus CDS
    CCDS34924.1
    UniProtKB/Swiss-Prot
    Q7Z388
    UniProtKB/TrEMBL
    A0A024R9F2
    Related
    ENSP00000389630.2, ENST00000414645.6
    Conserved Domains (1) summary
    pfam10034
    Location:62714
    Dpy19; Q-cell neuroblast polarization

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    94719708..94793836
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017013352.2XP_016868841.1  probable C-mannosyltransferase DPY19L4 isoform X5

  2. XM_005250895.3XP_005250952.1  probable C-mannosyltransferase DPY19L4 isoform X7

    See identical proteins and their annotated locations for XP_005250952.1

    Conserved Domains (1) summary
    pfam10034
    Location:1609
    Dpy19; Q-cell neuroblast polarization
  3. XM_017013356.2XP_016868845.1  probable C-mannosyltransferase DPY19L4 isoform X9

  4. XM_017013357.2XP_016868846.1  probable C-mannosyltransferase DPY19L4 isoform X10

  5. XM_005250894.4XP_005250951.2  probable C-mannosyltransferase DPY19L4 isoform X1

  6. XM_017013355.2XP_016868844.1  probable C-mannosyltransferase DPY19L4 isoform X8

    Conserved Domains (1) summary
    pfam10034
    Location:1578
    Dpy19; Q-cell neuroblast polarization
  7. XM_011516983.3XP_011515285.1  probable C-mannosyltransferase DPY19L4 isoform X2

    Conserved Domains (1) summary
    pfam10034
    Location:62681
    Dpy19; Q-cell neuroblast polarization
  8. XM_017013351.2XP_016868840.1  probable C-mannosyltransferase DPY19L4 isoform X4

  9. XM_017013353.2XP_016868842.1  probable C-mannosyltransferase DPY19L4 isoform X6

  10. XM_011516984.3XP_011515286.1  probable C-mannosyltransferase DPY19L4 isoform X3

    Conserved Domains (1) summary
    pfam10034
    Location:62672
    Dpy19; Q-cell neuroblast polarization
  11. XM_017013354.2XP_016868843.1  probable C-mannosyltransferase DPY19L4 isoform X7

    Conserved Domains (1) summary
    pfam10034
    Location:1609
    Dpy19; Q-cell neuroblast polarization
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