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SCARA5 scavenger receptor class A member 5 [ Homo sapiens (human) ]

Gene ID: 286133, updated on 1-Aug-2020

Summary

Official Symbol
SCARA5provided by HGNC
Official Full Name
scavenger receptor class A member 5provided by HGNC
Primary source
HGNC:HGNC:28701
See related
Ensembl:ENSG00000168079 MIM:611306
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Tesr; NET33
Expression
Broad expression in fat (RPKM 25.7), colon (RPKM 18.6) and 19 other tissues See more
Orthologs

Genomic context

See SCARA5 in Genome Data Viewer
Location:
8p21.1
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (27869883..27992673, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (27727399..27850369, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene establishment of sister chromatid cohesion N-acetyltransferase 2 Neighboring gene TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa pseudogene Neighboring gene PDZ binding kinase Neighboring gene SCARA5 intron CAGE-defined high expression enhancer Neighboring gene VISTA enhancer hs1741 Neighboring gene uncharacterized LOC105379342 Neighboring gene microRNA 4287 Neighboring gene nuclear GTPase, germinal center associated Neighboring gene elongator acetyltransferase complex subunit 3 Neighboring gene uncharacterized LOC105379343

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
NHGRI GWA Catalog

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23907, MGC45780

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ferritin receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
scavenger receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cellular iron ion homeostasis ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to heat IEA
Inferred from Electronic Annotation
more info
 
endocytosis ISS
Inferred from Sequence or Structural Similarity
more info
 
iron ion transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 
protein homotrimerization ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
scavenger receptor class A member 5
Names
scavenger receptor class A, member 5 (putative)
scavenger receptor hlg
testis expressed scavenger receptor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173833.6NP_776194.2  scavenger receptor class A member 5

    See identical proteins and their annotated locations for NP_776194.2

    Status: VALIDATED

    Source sequence(s)
    AC069113, AC104997
    Consensus CDS
    CCDS6064.1
    UniProtKB/Swiss-Prot
    Q6ZMJ2
    Related
    ENSP00000346990.3, ENST00000354914.8
    Conserved Domains (3) summary
    pfam01391
    Location:315373
    Collagen; Collagen triple helix repeat (20 copies)
    smart00202
    Location:393493
    SR; Scavenger receptor Cys-rich
    cl25732
    Location:90272
    SMC_N; RecF/RecN/SMC N terminal domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    27869883..27992673 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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