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SPDYE1 speedy/RINGO cell cycle regulator family member E1 [ Homo sapiens (human) ]

Gene ID: 285955, updated on 23-May-2020

Summary

Official Symbol
SPDYE1provided by HGNC
Official Full Name
speedy/RINGO cell cycle regulator family member E1provided by HGNC
Primary source
HGNC:HGNC:16408
See related
Ensembl:ENSG00000136206 MIM:617623
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SPDYE; Ringo1; WBSCR19; SPDYB2L2
Summary
This gene is located at chromosome 7p13 which is close to the Williams Beuren syndrome chromosome region 7q11.23. [provided by RefSeq, Jul 2008]
Expression
Broad expression in testis (RPKM 3.3), skin (RPKM 0.9) and 21 other tissues See more
Orthologs

Genomic context

See SPDYE1 in Genome Data Viewer
Location:
7p13
Exon count:
10
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (43997868..44011040)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (44038552..44049723)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene upregulator of cell proliferation Neighboring gene tubulin gamma 1 pseudogene Neighboring gene ubiquitin conjugating enzyme E2 D4 (putative) Neighboring gene RNA polymerase II subunit J4, pseudogene Neighboring gene RAS p21 protein activator 4C, pseudogene Neighboring gene long intergenic non-protein coding RNA 957 Neighboring gene microRNA 6837 Neighboring gene drebrin like

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General protein information

Preferred Names
putative WBSCR19-like protein 6
Names
Speedy E
Williams Beuren syndrome chromosome region 19 protein
speedy homolog E1
speedy protein E1
williams-Beuren syndrome chromosomal region 19 protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001378423.1NP_001365352.1  putative WBSCR19-like protein 6 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC004951
    Related
    ENSP00000499187.1, ENST00000652520.1
  2. NM_175064.4NP_778234.2  putative WBSCR19-like protein 6 isoform 2

    See identical proteins and their annotated locations for NP_778234.2

    Status: VALIDATED

    Source sequence(s)
    AC004951
    Consensus CDS
    CCDS5475.1
    UniProtKB/Swiss-Prot
    Q8NFV5
    Related
    ENSP00000258704.3, ENST00000258704.3
    Conserved Domains (1) summary
    pfam11357
    Location:153332
    Spy1; Cell cycle regulatory protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    43997868..44011040
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017012016.2XP_016867505.1  putative WBSCR19-like protein 6 isoform X2

  2. XM_017012015.1XP_016867504.1  putative WBSCR19-like protein 6 isoform X1

    Conserved Domains (1) summary
    pfam11357
    Location:193372
    Spy1; Cell cycle regulatory protein
  3. XM_017012017.2XP_016867506.1  putative WBSCR19-like protein 6 isoform X3

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NT_187561.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    18219..32911 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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