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HOXA-AS2 HOXA cluster antisense RNA 2 [ Homo sapiens (human) ]

Gene ID: 285943, updated on 11-Sep-2019

Summary

Official Symbol
HOXA-AS2provided by HGNC
Official Full Name
HOXA cluster antisense RNA 2provided by HGNC
Primary source
HGNC:HGNC:43745
See related
MIM:616068
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HOXA3as
Summary
This gene produces a long non-coding RNA that promotes cell proliferation. This transcript may interact with enhancer of zeste homolog 2 Polycomb repressive complex to repress gene expression. [provided by RefSeq, Dec 2017]
Expression
Broad expression in kidney (RPKM 3.0), lung (RPKM 2.4) and 18 other tissues See more
Orthologs

Genomic context

See HOXA-AS2 in Genome Data Viewer
Location:
7p15.2
Exon count:
4
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (27121919..27128760)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (27149730..27168372)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 2148 Neighboring gene HOXA transcript antisense RNA, myeloid-specific 1 Neighboring gene homeobox A2 Neighboring gene homeobox A3 Neighboring gene homeobox A4 Neighboring gene HOXA cluster antisense RNA 3 Neighboring gene homeobox A5 Neighboring gene homeobox A6

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association analyses identify variants in developmental genes associated with hypospadias.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Other Names

  • HOXA cluster antisense RNA 2 (non-protein coding)

Clone Names

  • FLJ18425, FLJ31668

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_122069.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC004080, AC010990

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    27121919..27128760
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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