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RPL7L1 ribosomal protein L7 like 1 [ Homo sapiens (human) ]

Gene ID: 285855, updated on 9-Feb-2020

Summary

Official Symbol
RPL7L1provided by HGNC
Official Full Name
ribosomal protein L7 like 1provided by HGNC
Primary source
HGNC:HGNC:21370
See related
Ensembl:ENSG00000146223 MIM:617417
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
dJ475N16.4
Expression
Ubiquitous expression in thyroid (RPKM 20.6), brain (RPKM 19.0) and 25 other tissues See more
Orthologs

Genomic context

See RPL7L1 in Genome Data Viewer
Location:
6p21.1
Exon count:
7
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (42879616..42889934)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (42847354..42857627)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene BRD4 interacting chromatin remodeling complex associated protein like Neighboring gene tubulin folding cofactor C Neighboring gene uncharacterized LOC401261 Neighboring gene uncharacterized LOC105375063 Neighboring gene chromosome 6 open reading frame 226

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC62004

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
blastocyst formation IEA
Inferred from Electronic Annotation
more info
 
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleolus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
60S ribosomal protein L7-like 1
Names
large ribosomal subunit protein uL30-like 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001366481.3NP_001353410.1  60S ribosomal protein L7-like 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) represents the longest transcript. Variants 1 and 4 both encode the same protein.
    Source sequence(s)
    AL035587
    Related
    ENSP00000418221.2, ENST00000493763.6
    Conserved Domains (1) summary
    TIGR01310
    Location:23255
    uL30_euk; 60S ribosomal protein uL30, eukaryotic form
  2. NM_198486.4NP_940888.3  60S ribosomal protein L7-like 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) and variant 4 encode the same protein.
    Source sequence(s)
    AL035587
    Consensus CDS
    CCDS4873.2
    UniProtKB/Swiss-Prot
    Q6DKI1
    UniProtKB/TrEMBL
    A0A024RD36
    Related
    ENSP00000346063.4, ENST00000304734.9
    Conserved Domains (1) summary
    TIGR01310
    Location:23255
    uL30_euk; 60S ribosomal protein uL30, eukaryotic form

RNA

  1. NR_134562.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site at an internal 5' exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AL035587
  2. NR_134563.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate 5' exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AL035587

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    42879616..42889934
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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