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TRBV12-4 T cell receptor beta variable 12-4 [ Homo sapiens (human) ]

Gene ID: 28576, updated on 17-Sep-2024

Summary

Official Symbol
TRBV12-4provided by HGNC
Official Full Name
T cell receptor beta variable 12-4provided by HGNC
Primary source
HGNC:HGNC:12186
See related
Ensembl:ENSG00000276953 IMGT/GENE-DB:TRBV12-4; AllianceGenome:HGNC:12186
Gene type
other
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TRBV124; TCRBV12S4; TCRBV8S2A1T
Summary
Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: partial on reference assembly
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Genomic context

See TRBV12-4 in Genome Data Viewer
Location:
7q34
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (142563799..142564245)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (143920664..143921110)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 (PATCHES) NW_003571040.1 (747559..748005)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene T cell receptor beta locus Neighboring gene T cell receptor beta variable 11-3 Neighboring gene T cell receptor beta variable 12-3 Neighboring gene T cell receptor beta variable 12-5 Neighboring gene T cell receptor beta variable 14

Genomic regions, transcripts, and products

General gene information

Other Names

  • V_segment translation product

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in adaptive immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in cell surface receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of T cell receptor complex IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_001333.2 

    Range
    398641..399087
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    142563799..142564245
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187562.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    567488..567934
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    143920664..143921110
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)