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SLC36A3 solute carrier family 36 member 3 [ Homo sapiens (human) ]

Gene ID: 285641, updated on 23-Nov-2021

Summary

Official Symbol
SLC36A3provided by HGNC
Official Full Name
solute carrier family 36 member 3provided by HGNC
Primary source
HGNC:HGNC:19659
See related
Ensembl:ENSG00000186334 MIM:608332
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PAT3; TRAMD2; tramdorin2
Expression
Restricted expression toward testis (RPKM 4.0) See more
Orthologs
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Genomic context

See SLC36A3 in Genome Data Viewer
Location:
5q33.1
Exon count:
11
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (151276358..151303766, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (150655919..150683327, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 69 Neighboring gene uncharacterized LOC105378230 Neighboring gene GM2 ganglioside activator Neighboring gene ATPase H+ transporting V1 subunit G1 pseudogene 5 Neighboring gene solute carrier family 36 member 2 Neighboring gene uncharacterized LOC105378234 Neighboring gene mediator complex subunit 13 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ16658, MGC119638, MGC119639, MGC119641

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables L-alanine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables L-proline transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables amino acid:proton symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables glycine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in L-alanine transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in glycine transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in proline transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in proton transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
proton-coupled amino acid transporter 3
Names
proton/amino acid transporter 3
solute carrier family 36 (proton/amino acid symporter), member 3
tramdorin 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145017.2NP_001138489.1  proton-coupled amino acid transporter 3 isoform 1

    See identical proteins and their annotated locations for NP_001138489.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC008385, BC101092
    Consensus CDS
    CCDS47316.1
    UniProtKB/Swiss-Prot
    Q495N2
    Related
    ENSP00000366942.3, ENST00000377713.3
    Conserved Domains (1) summary
    cl00456
    Location:41492
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  2. NM_181774.4NP_861439.3  proton-coupled amino acid transporter 3 isoform 2

    See identical proteins and their annotated locations for NP_861439.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the coding region compared to variant 1. The resulting protein (isoform 2) is shorter and has the identical N- and C-termini compared to isoform 1.
    Source sequence(s)
    AC008385, BC101095
    Consensus CDS
    CCDS4314.1
    UniProtKB/Swiss-Prot
    Q495N2
    Related
    ENSP00000334750.3, ENST00000335230.8
    Conserved Domains (1) summary
    cl00456
    Location:41451
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    151276358..151303766 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011537627.3XP_011535929.1  proton-coupled amino acid transporter 3 isoform X1

    Conserved Domains (1) summary
    cl00456
    Location:41425
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  2. XM_011537633.1XP_011535935.1  proton-coupled amino acid transporter 3 isoform X4

    Conserved Domains (1) summary
    cl00456
    Location:42288
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  3. XM_011537631.2XP_011535933.1  proton-coupled amino acid transporter 3 isoform X3

    See identical proteins and their annotated locations for XP_011535933.1

    Conserved Domains (1) summary
    cl00456
    Location:13336
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  4. XM_011537630.2XP_011535932.1  proton-coupled amino acid transporter 3 isoform X3

    See identical proteins and their annotated locations for XP_011535932.1

    Conserved Domains (1) summary
    cl00456
    Location:13336
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  5. XM_011537629.3XP_011535931.1  proton-coupled amino acid transporter 3 isoform X2

    Conserved Domains (1) summary
    cl00456
    Location:41327
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  6. XM_011537634.3XP_011535936.1  proton-coupled amino acid transporter 3 isoform X5

    Conserved Domains (1) summary
    cl00456
    Location:41163
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

RNA

  1. XR_427775.3 RNA Sequence

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