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ARL10 ADP ribosylation factor like GTPase 10 [ Homo sapiens (human) ]

Gene ID: 285598, updated on 13-Mar-2020

Summary

Official Symbol
ARL10provided by HGNC
Official Full Name
ADP ribosylation factor like GTPase 10provided by HGNC
Primary source
HGNC:HGNC:22042
See related
Ensembl:ENSG00000175414
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ARL10A
Expression
Ubiquitous expression in brain (RPKM 2.9), ovary (RPKM 2.2) and 22 other tissues See more
Orthologs

Genomic context

See ARL10 in Genome Data Viewer
Location:
5q35.2
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (176365468..176415096)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (175792477..175800934)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene SUMO interacting motifs containing 1 Neighboring gene BRCA1/BRCA2-containing complex subunit 3 pseudogene 1 Neighboring gene KIAA1191 Neighboring gene microRNA 1271 Neighboring gene NOP16 nucleolar protein Neighboring gene HIG1 hypoxia inducible domain family member 2A Neighboring gene clathrin light chain B Neighboring gene Fas associated factor family member 2 Neighboring gene collagen alpha-1(III) chain-like Neighboring gene ring finger protein 44 Neighboring gene cadherin related family member 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ39249

Gene Ontology Provided by GOA

Function Evidence Code Pubs
GTP binding IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ADP-ribosylation factor-like protein 10
Names
ADP-ribosylation factor-like 10A
ADP-ribosylation factor-like membrane-associated protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001317948.1NP_001304877.1  ADP-ribosylation factor-like protein 10 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC138956, BC059361
    UniProtKB/TrEMBL
    Q6PCE2
    Conserved Domains (1) summary
    cd04162
    Location:79250
    Arl9_Arfrp2_like; Arf-like 9 (Arl9)/Arfrp2-like GTPase
  2. NM_173664.6NP_775935.1  ADP-ribosylation factor-like protein 10 isoform 2

    See identical proteins and their annotated locations for NP_775935.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' coding region and 3' UTR compared to variant 1. The encoded isoform (2) has a distinct, shorter C-terminus than isoform 1.
    Source sequence(s)
    AC138956, BC059361, DR001833
    Consensus CDS
    CCDS4400.1
    UniProtKB/Swiss-Prot
    Q8N8L6
    UniProtKB/TrEMBL
    Q6PCE2
    Related
    ENSP00000308496.5, ENST00000310389.6
    Conserved Domains (2) summary
    cd04162
    Location:79237
    Arl9_Arfrp2_like; Arf-like 9 (Arl9)/Arfrp2-like GTPase
    pfam00071
    Location:80218
    Ras; Ras family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    176365468..176415096
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017009372.1XP_016864861.1  ADP-ribosylation factor-like protein 10 isoform X4

  2. XM_011534529.3XP_011532831.1  ADP-ribosylation factor-like protein 10 isoform X1

    Conserved Domains (1) summary
    cl21455
    Location:79187
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  3. XM_011534530.3XP_011532832.1  ADP-ribosylation factor-like protein 10 isoform X2

    Conserved Domains (1) summary
    cl21455
    Location:79190
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  4. XM_011534531.3XP_011532833.1  ADP-ribosylation factor-like protein 10 isoform X3

    Conserved Domains (1) summary
    cl21455
    Location:79188
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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