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FAM153A family with sequence similarity 153 member A [ Homo sapiens (human) ]

Gene ID: 285596, updated on 25-Jan-2022

Summary

Official Symbol
FAM153Aprovided by HGNC
Official Full Name
family with sequence similarity 153 member Aprovided by HGNC
Primary source
HGNC:HGNC:29940
See related
Ensembl:ENSG00000170074 AllianceGenome:HGNC:29940
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NY-REN-7
Expression
Biased expression in testis (RPKM 10.8), spleen (RPKM 4.8) and 7 other tissues See more
Orthologs
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Genomic context

See FAM153A in Genome Data Viewer
Location:
5q35.3
Exon count:
38
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (177694247..177783518, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (177138050..177210426, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene beta-1,4-galactosyltransferase 7 Neighboring gene SUMO interacting motifs containing 1 pseudogene Neighboring gene uncharacterized LOC107986489 Neighboring gene uncharacterized LOC100419951 Neighboring gene FAM83G pseudogene Neighboring gene uncharacterized LOC107986490

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ75901, KIAA0752

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
protein FAM153A
Names
NY REN 7 antigen
renal carcinoma antigen NY-REN-7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001394339.1NP_001381268.1  protein FAM153A

    Status: VALIDATED

    Source sequence(s)
    AC140125
    Related
    ENSP00000481950.1, ENST00000614127.4
  2. NM_173663.5NP_775934.3  protein FAM153A

    See identical proteins and their annotated locations for NP_775934.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the protein.
    Source sequence(s)
    AC140125, AF155097, DA217331
    Consensus CDS
    CCDS34305.1
    UniProtKB/Swiss-Prot
    Q9UHL3
    Related
    ENSP00000411506.3, ENST00000440605.7
    Conserved Domains (1) summary
    pfam15722
    Location:178310
    FAM153; FAM153 family

RNA

  1. NR_146226.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains multiple differences, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC138819, AC140125, DB306163
  2. NR_146227.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains multiple differences, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC138819, AC140125, DB306163

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    177694247..177783518 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017009359.1XP_016864848.1  protein FAM153A isoform X1

    UniProtKB/TrEMBL
    A0A087WYN1
    Conserved Domains (1) summary
    pfam15722
    Location:255387
    FAM153; FAM153 family
  2. XM_017009358.1XP_016864847.1  protein FAM153A isoform X1

    UniProtKB/TrEMBL
    A0A087WYN1
    Conserved Domains (1) summary
    pfam15722
    Location:255387
    FAM153; FAM153 family
  3. XM_017009364.1XP_016864853.1  protein FAM153A isoform X4

  4. XM_011534522.2XP_011532824.1  protein FAM153A isoform X6

    See identical proteins and their annotated locations for XP_011532824.1

    UniProtKB/Swiss-Prot
    Q9UHL3
    Conserved Domains (1) summary
    pfam15722
    Location:178310
    FAM153; FAM153 family
  5. XM_011534523.2XP_011532825.1  protein FAM153A isoform X6

    See identical proteins and their annotated locations for XP_011532825.1

    UniProtKB/Swiss-Prot
    Q9UHL3
    Conserved Domains (1) summary
    pfam15722
    Location:178310
    FAM153; FAM153 family
  6. XM_017009370.1XP_016864859.1  protein FAM153A isoform X6

    UniProtKB/Swiss-Prot
    Q9UHL3
    Conserved Domains (1) summary
    pfam15722
    Location:178310
    FAM153; FAM153 family
  7. XM_017009369.1XP_016864858.1  protein FAM153A isoform X6

    UniProtKB/Swiss-Prot
    Q9UHL3
    Conserved Domains (1) summary
    pfam15722
    Location:178310
    FAM153; FAM153 family
  8. XM_011534521.3XP_011532823.1  protein FAM153A isoform X6

    See identical proteins and their annotated locations for XP_011532823.1

    UniProtKB/Swiss-Prot
    Q9UHL3
    Conserved Domains (1) summary
    pfam15722
    Location:178310
    FAM153; FAM153 family
  9. XM_017009366.1XP_016864855.1  protein FAM153A isoform X6

    UniProtKB/Swiss-Prot
    Q9UHL3
    Conserved Domains (1) summary
    pfam15722
    Location:178310
    FAM153; FAM153 family
  10. XM_017009365.1XP_016864854.1  protein FAM153A isoform X5

  11. XM_017009363.1XP_016864852.1  protein FAM153A isoform X4

  12. XM_017009367.1XP_016864856.1  protein FAM153A isoform X6

    UniProtKB/Swiss-Prot
    Q9UHL3
    Conserved Domains (1) summary
    pfam15722
    Location:178310
    FAM153; FAM153 family
  13. XM_006714849.3XP_006714912.1  protein FAM153A isoform X6

    See identical proteins and their annotated locations for XP_006714912.1

    UniProtKB/Swiss-Prot
    Q9UHL3
    Related
    ENSP00000353887.6, ENST00000360669.10
    Conserved Domains (1) summary
    pfam15722
    Location:178310
    FAM153; FAM153 family
  14. XM_006714848.3XP_006714911.1  protein FAM153A isoform X6

    See identical proteins and their annotated locations for XP_006714911.1

    UniProtKB/Swiss-Prot
    Q9UHL3
    Conserved Domains (1) summary
    pfam15722
    Location:178310
    FAM153; FAM153 family
  15. XM_011534528.2XP_011532830.1  protein FAM153A isoform X7

    Conserved Domains (1) summary
    pfam15722
    Location:123255
    FAM153; FAM153 family
  16. XM_011534520.2XP_011532822.1  protein FAM153A isoform X2

    Conserved Domains (1) summary
    pfam15722
    Location:253385
    FAM153; FAM153 family
  17. XM_017009356.1XP_016864845.1  protein FAM153A isoform X1

    UniProtKB/TrEMBL
    A0A087WYN1
    Conserved Domains (1) summary
    pfam15722
    Location:255387
    FAM153; FAM153 family
  18. XM_017009354.1XP_016864843.1  protein FAM153A isoform X1

    UniProtKB/TrEMBL
    A0A087WYN1
    Conserved Domains (1) summary
    pfam15722
    Location:255387
    FAM153; FAM153 family
  19. XM_005265889.3XP_005265946.1  protein FAM153A isoform X1

    UniProtKB/TrEMBL
    A0A087WYN1
    Conserved Domains (1) summary
    pfam15722
    Location:255387
    FAM153; FAM153 family
  20. XM_017009360.1XP_016864849.1  protein FAM153A isoform X1

    UniProtKB/TrEMBL
    A0A087WYN1
    Conserved Domains (1) summary
    pfam15722
    Location:255387
    FAM153; FAM153 family
  21. XM_017009361.1XP_016864850.1  protein FAM153A isoform X1

    UniProtKB/TrEMBL
    A0A087WYN1
    Conserved Domains (1) summary
    pfam15722
    Location:255387
    FAM153; FAM153 family
  22. XM_017009357.1XP_016864846.1  protein FAM153A isoform X1

    UniProtKB/TrEMBL
    A0A087WYN1
    Conserved Domains (1) summary
    pfam15722
    Location:255387
    FAM153; FAM153 family
  23. XM_017009353.1XP_016864842.1  protein FAM153A isoform X1

    UniProtKB/TrEMBL
    A0A087WYN1
    Conserved Domains (1) summary
    pfam15722
    Location:255387
    FAM153; FAM153 family
  24. XM_017009352.1XP_016864841.1  protein FAM153A isoform X1

    UniProtKB/TrEMBL
    A0A087WYN1
    Conserved Domains (1) summary
    pfam15722
    Location:255387
    FAM153; FAM153 family
  25. XM_017009355.1XP_016864844.1  protein FAM153A isoform X1

    UniProtKB/TrEMBL
    A0A087WYN1
    Conserved Domains (1) summary
    pfam15722
    Location:255387
    FAM153; FAM153 family
  26. XM_017009362.1XP_016864851.1  protein FAM153A isoform X3

    Conserved Domains (1) summary
    pfam15722
    Location:207339
    FAM153; FAM153 family
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