FAM200B family with sequence similarity 200 member B [Homo sapiens (human)] - Gene

Summary

Official Symbol: FAM200Bprovided by HGNC
Official Full Name: family with sequence similarity 200 member Bprovided by HGNC
Primary source: HGNC:HGNC:27740
See related: Ensembl:ENSG00000237765
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: C4orf53
Expression: Ubiquitous expression in brain (RPKM 6.0), thyroid (RPKM 5.5) and 25 other tissues See more
Orthologs: all

Genomic context

Location:: 4p15.32

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
109.20190905	current	GRCh38.p13 (GCF_000001405.39)	4	NC_000004.12 (15651521..15690447)
105	previous assembly	GRCh37.p13 (GCF_000001405.25)	4	NC_000004.11 (15683352..15692070)

Chromosome 4 - NC_000004.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

HIV-1 interactions

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Replication interactions

Interaction	Pubs
Knockdown of family with sequence similarity 200, member B (FAM200B; LOC285550) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells	PubMed

Go to the HIV-1, Human Interaction Database

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

SGC31945 (e-PCR)
- UniSTS:99844

SHGC-59190 (e-PCR)
- UniSTS:5125

NoName (e-PCR)
- UniSTS:484627

SHGC-53928 (e-PCR)
- UniSTS:76878

RH98624 (e-PCR)
- UniSTS:89698

SHGC-67307 (e-PCR)
- UniSTS:89991

SHGC-50493 (e-PCR)
- UniSTS:60043

RH94215 (e-PCR)
- UniSTS:90079

WI-11209 (e-PCR)
- UniSTS:28387

STS-H96902 (e-PCR)
- UniSTS:69866

Homology

Homologs of the FAM200B gene: The FAM200B gene is conserved in chimpanzee, Rhesus monkey, dog, and cow.
Orthologs from Annotation Pipeline: 59 organisms have orthologs with human gene FAM200B
Orthologs

Gene Ontology Provided by GOA

Component	Evidence Code	Pubs
nucleoplasm	IBA Inferred from Biological aspect of Ancestor more info	PubMed

General protein information

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Preferred Names: protein FAM200B

Names: Putative protein FAM200B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.