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FRYL FRY like transcription coactivator [ Homo sapiens (human) ]

Gene ID: 285527, updated on 22-Jan-2020

Summary

Official Symbol
FRYLprovided by HGNC
Official Full Name
FRY like transcription coactivatorprovided by HGNC
Primary source
HGNC:HGNC:29127
See related
Ensembl:ENSG00000075539
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MOR2; AF4p12; KIAA0826
Expression
Ubiquitous expression in colon (RPKM 15.9), lymph node (RPKM 5.8) and 24 other tissues See more
Orthologs

Genomic context

See FRYL in Genome Data Viewer
Location:
4p11
Exon count:
69
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (48497357..48780323, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (48499380..48782329, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chr4.1483 Neighboring gene solute carrier family 10 member 4 Neighboring gene zygote arrest 1 Neighboring gene RNA, U5E small nuclear 3, pseudogene Neighboring gene OCIAD1 antisense RNA 1 Neighboring gene OCIA domain containing 1 Neighboring gene OCIA domain containing 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ16177, DKFZp686E205

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cell morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cell cortex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
protein furry homolog-like
Names
ALL1-fused gene from chromosome 4p12 protein
FRY-like
furry homolog-like
furry-like
mor2 cell polarity protein homolog

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015030.2NP_055845.1  protein furry homolog-like

    See identical proteins and their annotated locations for NP_055845.1

    Status: VALIDATED

    Source sequence(s)
    AC068037, AC096952
    Consensus CDS
    CCDS43227.1
    UniProtKB/Swiss-Prot
    O94915
    UniProtKB/TrEMBL
    B3KXG5, Q6ZR29
    Related
    ENSP00000351113.4, ENST00000358350.9
    Conserved Domains (3) summary
    pfam14222
    Location:117649
    MOR2-PAG1_N; Cell morphogenesis N-terminal
    pfam14225
    Location:20012254
    MOR2-PAG1_C; Cell morphogenesis C-terminal
    pfam14228
    Location:6871859
    MOR2-PAG1_mid; Cell morphogenesis central region

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    48497357..48780323 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024453991.1XP_024309759.1  protein furry homolog-like isoform X6

    Conserved Domains (3) summary
    pfam14222
    Location:117664
    MOR2-PAG1_N; Cell morphogenesis N-terminal
    pfam14225
    Location:20162269
    MOR2-PAG1_C; Cell morphogenesis C-terminal
    pfam14228
    Location:7021874
    MOR2-PAG1_mid; Cell morphogenesis central region
  2. XM_005248090.5XP_005248147.1  protein furry homolog-like isoform X6

    See identical proteins and their annotated locations for XP_005248147.1

    Conserved Domains (3) summary
    pfam14222
    Location:117664
    MOR2-PAG1_N; Cell morphogenesis N-terminal
    pfam14225
    Location:20162269
    MOR2-PAG1_C; Cell morphogenesis C-terminal
    pfam14228
    Location:7021874
    MOR2-PAG1_mid; Cell morphogenesis central region
  3. XM_024453993.1XP_024309761.1  protein furry homolog-like isoform X7

    Conserved Domains (3) summary
    pfam14222
    Location:117649
    MOR2-PAG1_N; Cell morphogenesis N-terminal
    pfam14225
    Location:20012254
    MOR2-PAG1_C; Cell morphogenesis C-terminal
    pfam14228
    Location:6871859
    MOR2-PAG1_mid; Cell morphogenesis central region
  4. XM_011513683.3XP_011511985.1  protein furry homolog-like isoform X6

    See identical proteins and their annotated locations for XP_011511985.1

    Conserved Domains (3) summary
    pfam14222
    Location:117664
    MOR2-PAG1_N; Cell morphogenesis N-terminal
    pfam14225
    Location:20162269
    MOR2-PAG1_C; Cell morphogenesis C-terminal
    pfam14228
    Location:7021874
    MOR2-PAG1_mid; Cell morphogenesis central region
  5. XM_017008046.2XP_016863535.1  protein furry homolog-like isoform X7

    UniProtKB/Swiss-Prot
    O94915
    Conserved Domains (3) summary
    pfam14222
    Location:117649
    MOR2-PAG1_N; Cell morphogenesis N-terminal
    pfam14225
    Location:20012254
    MOR2-PAG1_C; Cell morphogenesis C-terminal
    pfam14228
    Location:6871859
    MOR2-PAG1_mid; Cell morphogenesis central region
  6. XM_024453990.1XP_024309758.1  protein furry homolog-like isoform X6

    Conserved Domains (3) summary
    pfam14222
    Location:117664
    MOR2-PAG1_N; Cell morphogenesis N-terminal
    pfam14225
    Location:20162269
    MOR2-PAG1_C; Cell morphogenesis C-terminal
    pfam14228
    Location:7021874
    MOR2-PAG1_mid; Cell morphogenesis central region
  7. XM_024453994.1XP_024309762.1  protein furry homolog-like isoform X7

    Conserved Domains (3) summary
    pfam14222
    Location:117649
    MOR2-PAG1_N; Cell morphogenesis N-terminal
    pfam14225
    Location:20012254
    MOR2-PAG1_C; Cell morphogenesis C-terminal
    pfam14228
    Location:6871859
    MOR2-PAG1_mid; Cell morphogenesis central region
  8. XM_011513680.3XP_011511982.2  protein furry homolog-like isoform X2

    Conserved Domains (3) summary
    pfam14222
    Location:209756
    MOR2-PAG1_N; Cell morphogenesis N-terminal
    pfam14225
    Location:21072360
    MOR2-PAG1_C; Cell morphogenesis C-terminal
    pfam14228
    Location:7941965
    MOR2-PAG1_mid; Cell morphogenesis central region
  9. XM_024453988.1XP_024309756.1  protein furry homolog-like isoform X1

    Conserved Domains (3) summary
    pfam14222
    Location:209756
    MOR2-PAG1_N; Cell morphogenesis N-terminal
    pfam14225
    Location:21082361
    MOR2-PAG1_C; Cell morphogenesis C-terminal
    pfam14228
    Location:7941966
    MOR2-PAG1_mid; Cell morphogenesis central region
  10. XM_024453989.1XP_024309757.1  protein furry homolog-like isoform X4

    Conserved Domains (3) summary
    pfam14222
    Location:209741
    MOR2-PAG1_N; Cell morphogenesis N-terminal
    pfam14225
    Location:20932346
    MOR2-PAG1_C; Cell morphogenesis C-terminal
    pfam14228
    Location:7791951
    MOR2-PAG1_mid; Cell morphogenesis central region
  11. XM_011513681.3XP_011511983.2  protein furry homolog-like isoform X3

    Conserved Domains (3) summary
    pfam14222
    Location:209756
    MOR2-PAG1_N; Cell morphogenesis N-terminal
    pfam14225
    Location:21082361
    MOR2-PAG1_C; Cell morphogenesis C-terminal
    pfam14228
    Location:7941966
    MOR2-PAG1_mid; Cell morphogenesis central region
  12. XM_011513682.3XP_011511984.2  protein furry homolog-like isoform X5

    Conserved Domains (3) summary
    pfam14222
    Location:209741
    MOR2-PAG1_N; Cell morphogenesis N-terminal
    pfam14225
    Location:20932346
    MOR2-PAG1_C; Cell morphogenesis C-terminal
    pfam14228
    Location:7791951
    MOR2-PAG1_mid; Cell morphogenesis central region
  13. XM_024453992.1XP_024309760.1  protein furry homolog-like isoform X6

    Conserved Domains (3) summary
    pfam14222
    Location:117664
    MOR2-PAG1_N; Cell morphogenesis N-terminal
    pfam14225
    Location:20162269
    MOR2-PAG1_C; Cell morphogenesis C-terminal
    pfam14228
    Location:7021874
    MOR2-PAG1_mid; Cell morphogenesis central region
  14. XM_005248093.5XP_005248150.1  protein furry homolog-like isoform X8

    See identical proteins and their annotated locations for XP_005248150.1

    Related
    ENSP00000422408.3, ENST00000507873.7
    Conserved Domains (2) summary
    pfam14225
    Location:10321285
    MOR2-PAG1_C; Cell morphogenesis C-terminal
    pfam14228
    Location:197890
    MOR2-PAG1_mid; Cell morphogenesis central region
  15. XM_011513684.3XP_011511986.1  protein furry homolog-like isoform X8

    See identical proteins and their annotated locations for XP_011511986.1

    Conserved Domains (2) summary
    pfam14225
    Location:10321285
    MOR2-PAG1_C; Cell morphogenesis C-terminal
    pfam14228
    Location:197890
    MOR2-PAG1_mid; Cell morphogenesis central region
  16. XM_011513685.3XP_011511987.2  protein furry homolog-like isoform X9

    Related
    ENSP00000421584.1, ENST00000507711.5
    Conserved Domains (2) summary
    pfam14222
    Location:209756
    MOR2-PAG1_N; Cell morphogenesis N-terminal
    pfam14228
    Location:7941559
    MOR2-PAG1_mid; Cell morphogenesis central region

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001039751.1: Suppressed sequence

    Description
    NM_001039751.1: This RefSeq was temporarily suppressed because it encoded a much smaller protein than the full-length protein. It may represent a valid splicing variant but currently there are not sufficient data to support this tra
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