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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_013072.2Â RefSeqGene
- Range
-
5001..36177
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_869
mRNA and Protein(s)
-
NM_001164673.2 → NP_001158145.1  protein Dok-7 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence and uses an alternate splice site in the central coding region compared to variant 4, that causes a frameshift. The encoded isoform (2) differs in the central region and has a shorter and distinct C-terminus compared to isoform 4.
- Source sequence(s)
-
AK091037, BM684814, DA205628
- Consensus CDS
-
CCDS54717.1
- UniProtKB/Swiss-Prot
-
Q18PE1
- Related
- ENSP00000423614.1, ENST00000507039.5
- Conserved Domains (3) summary
-
- cd14677
Location:6 → 107
- PH_DOK7; Pleckstrin homology (PH) domain of Downstream of tyrosine kinase 7
- pfam00169
Location:8 → 108
- PH; PH domain
- cl17171
Location:108 → 174
- PH-like; Pleckstrin homology-like domain
-
NM_001256896.2 → NP_001243825.1  protein Dok-7 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate internal promoter and differs in the 3' UTR and coding sequence compared to variant 4. The encoded isoform (3) is significantly shorter at the N-terminus and has a shorter and distinct C-terminus compared to isoform 4.
- Source sequence(s)
-
AK091037, AK096456, BM684814, DA823926
- Consensus CDS
-
CCDS87206.1
- UniProtKB/Swiss-Prot
-
Q18PE1
- UniProtKB/TrEMBL
- A0A1W2PRA3, Q8N1M3
- Related
- ENSP00000492194.1, ENST00000515886.5
-
NM_001301071.2 → NP_001288000.1  protein Dok-7 isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) encodes the longest isoform (4).
- Source sequence(s)
-
AK075037, AL590235, BC141852, DA205628
- UniProtKB/Swiss-Prot
-
Q18PE1
- Conserved Domains (2) summary
-
- cd13165
Location:108 → 208
- PTB_DOK7; Downstream of tyrosine kinase 7 phosphotyrosine-binding domain (PTBi)
- cd14677
Location:6 → 107
- PH_DOK7; Pleckstrin homology (PH) domain of Downstream of tyrosine kinase 7
-
NM_001363811.2 → NP_001350740.1  protein Dok-7 isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks two alternate exons compared to variant 4. The resulting isoform (5) has the same N- and C-termini but is shorter compared to isoform 4.
- Source sequence(s)
-
AL590235
- Consensus CDS
-
CCDS87205.1
- UniProtKB/TrEMBL
-
A0A2R8Y701
- Related
- ENSP00000495701.1, ENST00000643608.1
- Conserved Domains (1) summary
-
- cl17171
Location:6 → 33
- PH-like; Pleckstrin homology-like domain
-
NM_173660.5 → NP_775931.3  protein Dok-7 isoform 1
See identical proteins and their annotated locations for NP_775931.3
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) differs in the 3' UTR and coding sequence compared to variant 4. The resulting isoform (1) has a shorter and distinct C-terminus compared to isoform 4.
- Source sequence(s)
-
AK091037, BC141852, BM684814, DA205628
- Consensus CDS
-
CCDS3370.2
- UniProtKB/Swiss-Prot
- Q18PE1, Q8NBC1
- Related
- ENSP00000344432.5, ENST00000340083.6
- Conserved Domains (2) summary
-
- cd13165
Location:108 → 208
- PTB_DOK7; Downstream of tyrosine kinase 7 phosphotyrosine-binding domain (PTBi)
- cd14677
Location:6 → 107
- PH_DOK7; Pleckstrin homology (PH) domain of Downstream of tyrosine kinase 7
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000004.12Â Reference GRCh38.p14 Primary Assembly
- Range
-
3463306..3501482
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011513435.3 → XP_011511737.1  protein Dok-7 isoform X1
- Conserved Domains (2) summary
-
- cd13165
Location:108 → 208
- PTB_DOK7; Downstream of tyrosine kinase 7 phosphotyrosine-binding domain (PTBi)
- cd14677
Location:6 → 107
- PH_DOK7; Pleckstrin homology (PH) domain of Downstream of tyrosine kinase 7
-
XM_047450078.1 → XP_047306034.1  protein Dok-7 isoform X2
-
XM_047450079.1 → XP_047306035.1  protein Dok-7 isoform X3
-
XM_047450080.1 → XP_047306036.1  protein Dok-7 isoform X4
-
XM_047450081.1 → XP_047306037.1  protein Dok-7 isoform X5
- UniProtKB/TrEMBL
-
A0A1W2PRA3
Alternate T2T-CHM13v2.0
Genomic
-
NC_060928.1Â Alternate T2T-CHM13v2.0
- Range
-
3463090..3501240
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)