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GPR32 G protein-coupled receptor 32 [ Homo sapiens (human) ]

Gene ID: 2854, updated on 9-Jan-2022

Summary

Official Symbol
GPR32provided by HGNC
Official Full Name
G protein-coupled receptor 32provided by HGNC
Primary source
HGNC:HGNC:4487
See related
Ensembl:ENSG00000142511 MIM:603195
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RVDR1
Summary
This gene is intronless and encodes a member of the G-protein coupled receptor 1 family. The encoded protein binds to resolvin D1 and lipoxin A4 and has been linked to pulmonary inflammation. A related pseudogene has been identified on chromosome 19. [provided by RefSeq, Nov 2012]
Orthologs
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Genomic context

See GPR32 in Genome Data Viewer
Location:
19q13.33
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (50770464..50771732)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (51273721..51274989)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chr19.5690 Neighboring gene GPR32 pseudogene 1 Neighboring gene origin of replication 20mer1 Neighboring gene uncharacterized LOC105372440

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables N-formyl peptide receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables complement receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of plasma membrane TAS
Traceable Author Statement
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
probable G-protein coupled receptor 32
Names
resolvin D1 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001506.2NP_001497.1  probable G-protein coupled receptor 32

    See identical proteins and their annotated locations for NP_001497.1

    Status: REVIEWED

    Source sequence(s)
    AC010325, BC095544
    Consensus CDS
    CCDS12801.1
    UniProtKB/Swiss-Prot
    O75388
    UniProtKB/TrEMBL
    H9NIL6
    Related
    ENSP00000270590.3, ENST00000270590.4
    Conserved Domains (1) summary
    pfam00001
    Location:60316
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    50770464..50771732
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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