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ZNF852 zinc finger protein 852 [ Homo sapiens (human) ]

Gene ID: 285346, updated on 25-Jan-2022

Summary

Official Symbol
ZNF852provided by HGNC
Official Full Name
zinc finger protein 852provided by HGNC
Primary source
HGNC:HGNC:27713
See related
Ensembl:ENSG00000178917 AllianceGenome:HGNC:27713
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2021]
Annotation information
Annotation category: suggests misassembly
Expression
Ubiquitous expression in prostate (RPKM 1.1), spleen (RPKM 1.0) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF852 in Genome Data Viewer
Location:
3p21.31
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (44491766..44510617, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (44540229..44552109, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 694 Neighboring gene zinc finger protein 445 Neighboring gene uncharacterized LOC101928529 Neighboring gene zinc finger protein 852 pseudogene Neighboring gene EI24 pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 852
Names
putative zinc finger protein 852

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001287349.3NP_001274278.1  zinc finger protein 852

    Status: VALIDATED

    Source sequence(s)
    AC099669, AK296954
    UniProtKB/Swiss-Prot
    Q6ZMS4
    Related
    ENSP00000389841.2, ENST00000436261.6
    Conserved Domains (5) summary
    cd07765
    Location:847
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:156514
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:299321
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:453477
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    44491766..44510617 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 PATCHES

Genomic

  1. NW_009646197.1 Reference GRCh38.p13 PATCHES

    Range
    17120..35971 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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