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DUSP28 dual specificity phosphatase 28 [ Homo sapiens (human) ]

Gene ID: 285193, updated on 23-Nov-2021

Summary

Official Symbol
DUSP28provided by HGNC
Official Full Name
dual specificity phosphatase 28provided by HGNC
Primary source
HGNC:HGNC:33237
See related
Ensembl:ENSG00000188542
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
VHP; DUSP26
Expression
Ubiquitous expression in testis (RPKM 1.8), bone marrow (RPKM 1.4) and 25 other tissues See more
Orthologs
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Genomic context

See DUSP28 in Genome Data Viewer
Location:
2q37.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (240559239..240565256)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (241499471..241504673)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100130449 Neighboring gene glypican 1 Neighboring gene microRNA 149 Neighboring gene ankyrin repeat and MYND domain containing 1 Neighboring gene Sharpr-MPRA regulatory region 11390 Neighboring gene conserved acetylation island sequence C08 enhancer Neighboring gene arginyl aminopeptidase like 1 Neighboring gene Sharpr-MPRA regulatory region 11586 Neighboring gene CAPN10 divergent transcript

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein serine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein tyrosine/serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in dephosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in peptidyl-tyrosine dephosphorylation IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
dual specificity phosphatase 28
NP_001028747.1
NP_001357394.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033575.1NP_001028747.1  dual specificity phosphatase 28

    See identical proteins and their annotated locations for NP_001028747.1

    Status: VALIDATED

    Source sequence(s)
    AC124862, BC036198, BG656420, BQ777661
    Consensus CDS
    CCDS33418.1
    UniProtKB/Swiss-Prot
    Q4G0W2
    Related
    ENSP00000344235.2, ENST00000343217.6
    Conserved Domains (1) summary
    cd14574
    Location:19158
    DUSP28; dual specificity protein phosphatase 28
  2. NM_001370465.2NP_001357394.1  dual specificity phosphatase 28

    Status: VALIDATED

    Source sequence(s)
    AC124862
    Related
    ENSP00000385885.2, ENST00000405954.2
    Conserved Domains (1) summary
    cd14574
    Location:19158
    DUSP28; dual specificity protein phosphatase 28

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    240559239..240565256
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_002959284.1 RNA Sequence

  2. XR_002959285.1 RNA Sequence

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