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dgoD D-galactonate dehydratase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 2847765, updated on 17-Jul-2025
Official Symbol
dgoD
Official Full Name
D-galactonate dehydratase
Primary source
ECOCYC:GB4478
Locus tag
b4478
See related
ASAP:ABE-0174106
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
b3692; ECK3684; yidU
Summary
A genome sequence error, now repaired, previously fused dgoA and dgoD. [More information is available at EcoGene: EG20050]. D-galactonate dehydratase catalyzes the first step in the degradation of D-galactonate, the dehydration of D-galactonate to form 2-dehydro-3-deoxygalactonate . [More information is available at EcoCyc: GB4478].
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Sequence:
NC_000913.3 (3871850..3872998, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF3748 domain-containing galacturonate catabolism protein YidR Neighboring gene colicin M resistance protein Neighboring gene D-galactonate:H(+) symporter Neighboring gene 2-dehydro-3-deoxy-6-phosphogalactonate aldolase Neighboring gene 2-dehydro-3-deoxygalactonokinase Neighboring gene DNA-binding transcriptional regulator DgoR Neighboring gene putative lipoprotein YidX

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A functionally diverse enzyme superfamily that abstracts the alpha protons of carboxylic acids. Babbitt PC, et al. Science, 1995 Feb 24. PMID 7855594
  2. The utilisation of D-galactonate and D-2-oxo-3-deoxygalactonate by Escherichia coli K-12. Biochemical and genetical studies. Cooper RA. Arch Microbiol, 1978 Aug 1. PMID 211976
  3. D-Galactonate utilisation by enteric bacteria. The catabolic pathway in Escherichia coli. Deacon J, et al. FEBS Lett, 1977 May 15. PMID 324806
  4. Molecular and Functional Insights into the Regulation of d-Galactonate Metabolism by the Transcriptional Regulator DgoR in Escherichia coli. Singh B, et al. J Bacteriol, 2019 Feb 15. PMID 30455279, Free PMC Article
  5. DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication. Burland V, et al. Genomics, 1993 Jun. PMID 7686882

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on complete protein
    Title: A functionally diverse enzyme superfamily that abstracts the alpha protons of carboxylic acids.
Submit: New GeneRIF Correction

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables galactonate dehydratase activity IDA
Inferred from Direct Assay
more info
  
enables hydro-lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in D-galactonate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within D-galactonate catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Preferred Names
D-galactonate dehydratase
YP_026237.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3871850..3872998 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_026237.1 D-galactonate dehydratase

    See identical proteins and their annotated locations for YP_026237.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A418GGR6, A0A8S7XIN4
    Conserved Domains (1) summary
    PRK14017
    Location:1 → 382
    PRK14017; galactonate dehydratase; Provisional
Nucleotide Protein
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Gene LinkOut

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