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ldrA small toxic polypeptide LdrA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 2847733, updated on 6-May-2021

Summary

Gene symbol
ldrA
Gene description
small toxic polypeptide LdrA
Primary source
ASAP:ABE-0047280
Locus tag
b4419
See related
ECOCYC:G0-9602
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1204
Summary
ldrA is one of a set of four Long Direct Repeats (LDRs), one of which has been shown to code for the toxin portion of a toxin-antitoxin pair. ldrA, ldrB and ldrC are clustered together as tandem repeats, with ldrD elsewhere on the genome. [More information is available at EcoCyc: G0-9602].
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Genomic context

Sequence:
NC_000913.3 (1269168..1269275, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene transglutaminase-like/TPR repeat-containing protein Neighboring gene 3-deoxy-D-manno-octulosonate 8-phosphate synthase Neighboring gene ncRNA Neighboring gene small toxic polypeptide LdrB

General gene information

Gene Ontology Provided by GO

Process Evidence Code Pubs
acts_upstream_of_or_within cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within programmed cell death ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
small toxic polypeptide LdrA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1269168..1269275 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_025297.1 small toxic polypeptide LdrA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for YP_025297.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0DPD0, P0DPD1
    Conserved Domains (1) summary
    pfam13940
    Location:135
    Ldr_toxin; Toxin Ldr, type I toxin-antitoxin system
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