U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

glcF glycolate dehydrogenase, [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 2847717, updated on 10-Dec-2025
Official Symbol
glcF
Official Full Name
glycolate dehydrogenase,
Primary source
ECOCYC:G0-8601
Locus tag
b4467
See related
ASAP:ABE-0174097
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
b2978; ECK2972; gox; yghL
Summary
GlcF could only be detected as a membrane-associated protein . [More information is available at EcoCyc: G0-8601].
NEW
Try the new Gene table
Try the new Transcript table
Sequence:
NC_000913.3 (3124236..3125459, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene malate synthase G Neighboring gene putative heme-binding protein GlcG Neighboring gene glycolate dehydrogenase, predicted FAD-binding subunit Neighboring gene glycolate dehydrogenase, predicted FAD-linked subunit

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Glycolate oxidoreductase in Escherichia coli. Lord JM. Biochim Biophys Acta, 1972 May 25. PMID 4557653
  2. The intracellular localization of glycolate oxidoreductase in Escherichia coli. Sallal AK, et al. FEBS Lett, 1989 Dec 4. PMID 2689218
  3. The gene yghK linked to the glc operon of Escherichia coli encodes a permease for glycolate that is structurally and functionally similar to L-lactate permease. Núñez MF, et al. Microbiology (Reading), 2001 Apr. PMID 11283302
  4. Cross-induction of glc and ace operons of Escherichia coli attributable to pathway intersection. Characterization of the glc promoter. Pellicer MT, et al. J Biol Chem, 1999 Jan 15. PMID 9880556
  5. glc locus of Escherichia coli: characterization of genes encoding the subunits of glycolate oxidase and the glc regulator protein. Pellicer MT, et al. J Bacteriol, 1996 Apr. PMID 8606183, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables D-lactate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycolate dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycolate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycolate dehydrogenase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glycolate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within glycolate catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
glycolate dehydrogenase,
YP_026190.1

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3124236..3125459 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_026190.1 glycolate dehydrogenase, [Fe-S] subunit

    See identical proteins and their annotated locations for YP_026190.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A8S7EAM1
    Conserved Domains (1) summary
    PRK11274
    Location:1 → 404
    glcF; glycolate oxidase subunit GlcF
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.