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RIMKLA ribosomal modification protein rimK like family member A [ Homo sapiens (human) ]

Gene ID: 284716, updated on 8-Jul-2021

Summary

Official Symbol
RIMKLAprovided by HGNC
Official Full Name
ribosomal modification protein rimK like family member Aprovided by HGNC
Primary source
HGNC:HGNC:28725
See related
Ensembl:ENSG00000177181 MIM:618949
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NAAGS; FAM80A; NAAGS2; NAAGS-II
Expression
Biased expression in brain (RPKM 2.6), colon (RPKM 1.6) and 10 other tissues See more
Orthologs
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Genomic context

See RIMKLA in Genome Data Viewer
Location:
1p34.2
Exon count:
5
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (42380792..42425813)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (42846463..42889903)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 9331 Neighboring gene forkhead box J3 Neighboring gene ribosomal protein S15a pseudogene 8 Neighboring gene zinc finger MYND-type containing 12 Neighboring gene coiled-coil domain containing 30 Neighboring gene phosphopantothenoylcysteine synthetase

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC47816

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables N-acetyl-L-aspartate-L-glutamate ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables N-acetyl-L-aspartate-L-glutamate ligase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables N-acetyl-L-aspartate-L-glutamate ligase activity TAS
Traceable Author Statement
more info
 
enables ligase activity, forming carbon-nitrogen bonds IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular protein modification process IEA
Inferred from Electronic Annotation
more info
 
involved_in glutamine family amino acid metabolic process TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
N-acetylaspartylglutamate synthase A
Names
N-acetylaspartyl-glutamate synthetase A
N-acetylaspartylglutamate synthetase II
N-acetylaspartylglutamylglutamate synthase A
NAAG synthetase A
RP11-157D18.1
family with sequence similarity 80, member A
ribosomal protein S6 modification-like protein A
NP_775913.2
XP_006710648.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173642.4NP_775913.2  N-acetylaspartylglutamate synthase A

    See identical proteins and their annotated locations for NP_775913.2

    Status: VALIDATED

    Source sequence(s)
    AL513331, BC039737, BX094947, DR000262
    Consensus CDS
    CCDS466.2
    UniProtKB/Swiss-Prot
    Q8IXN7
    Related
    ENSP00000414330.2, ENST00000431473.4
    Conserved Domains (1) summary
    cl17255
    Location:5298
    CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    42380792..42425813
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006710585.3XP_006710648.1  N-acetylaspartylglutamate synthase A isoform X1

    Conserved Domains (2) summary
    pfam16508
    Location:67108
    NIBRIN_BRCT_II; Second BRCT domain on Nijmegen syndrome breakage protein
    cl17255
    Location:110176
    ATP-grasp_4; ATP-grasp domain
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