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OR14A16 olfactory receptor family 14 subfamily A member 16 [ Homo sapiens (human) ]

Gene ID: 284532, updated on 22-Sep-2022

Summary

Official Symbol
OR14A16provided by HGNC
Official Full Name
olfactory receptor family 14 subfamily A member 16provided by HGNC
Primary source
HGNC:HGNC:15022
See related
Ensembl:ENSG00000196772 AllianceGenome:HGNC:15022
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR5AT1
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR14A16 in Genome Data Viewer
Location:
1q44
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (247814660..247824119, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (247245514..247254979, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (247977962..247987421, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 1 subfamily C member 1 Neighboring gene olfactory receptor family 9 subfamily H member 1 pseudogene Neighboring gene hydroxysteroid 17-beta dehydrogenase 7 pseudogene 1 Neighboring gene olfactory receptor family 6 subfamily R member 1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 14A16
Names
olfactory receptor 5AT1
olfactory receptor OR1-45
olfactory receptor, family 5, subfamily AT, member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_053131.1 RefSeqGene

    Range
    5130..6059
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001001966.2NP_001001966.1  olfactory receptor 14A16

    See identical proteins and their annotated locations for NP_001001966.1

    Status: REVIEWED

    Source sequence(s)
    AC099571
    Consensus CDS
    CCDS31097.1
    UniProtKB/Swiss-Prot
    Q6IF96, Q8NHC5
    Related
    ENSP00000493024.1, ENST00000641093.1
    Conserved Domains (2) summary
    pfam00001
    Location:39287
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:29295
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    247814660..247824119 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    247245514..247254979 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)