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SLC25A42 solute carrier family 25 member 42 [ Homo sapiens (human) ]

Gene ID: 284439, updated on 5-Aug-2018

Summary

Official Symbol
SLC25A42provided by HGNC
Official Full Name
solute carrier family 25 member 42provided by HGNC
Primary source
HGNC:HGNC:28380
See related
Ensembl:ENSG00000181035 MIM:610823; Vega:OTTHUMG00000183280
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This gene encodes a solute carrier family 25 protein. Solute carrier family 25 proteins are localized to mitochondria and play critical roles in the transport of molecules across the inner mitochondrial membrane. The encoded protein is a mitochondrial transporter for coenzyme A (CoA) and adenosine 3',5'-diphosphate. [provided by RefSeq, Feb 2012]
Expression
Broad expression in kidney (RPKM 18.3), liver (RPKM 12.3) and 24 other tissues See more
Orthologs

Genomic context

See SLC25A42 in Genome Data Viewer
Location:
19p13.11
Exon count:
10
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 19 NC_000019.10 (19063961..19113030)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (19174776..19223839)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 70, pseudogene Neighboring gene SURP and G-patch domain containing 2 Neighboring gene armadillo repeat containing 6 Neighboring gene transmembrane protein 161A Neighboring gene BORCS8-MEF2B readthrough Neighboring gene myocyte enhancer factor 2B

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ54826, MGC26694

Gene Ontology Provided by GOA

Process Evidence Code Pubs
ADP transport IDA
Inferred from Direct Assay
more info
PubMed 
AMP transport IDA
Inferred from Direct Assay
more info
PubMed 
ATP transport IDA
Inferred from Direct Assay
more info
PubMed 
coenzyme A transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
nucleus HDA PubMed 

General protein information

Preferred Names
mitochondrial coenzyme A transporter SLC25A42

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_050576.1 RefSeqGene

    Range
    5001..54070
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001321544.1NP_001308473.1  mitochondrial coenzyme A transporter SLC25A42

    Status: REVIEWED

    Source sequence(s)
    AC002126, AC003038, AC004143, BX099926
    Consensus CDS
    CCDS32966.1
    UniProtKB/Swiss-Prot
    Q86VD7
    UniProtKB/TrEMBL
    A0A024R7K2
    Conserved Domains (1) summary
    cl28162
    Location:34295
    Mito_carr; Mitochondrial carrier protein
  2. NM_178526.4NP_848621.2  mitochondrial coenzyme A transporter SLC25A42

    See identical proteins and their annotated locations for NP_848621.2

    Status: REVIEWED

    Source sequence(s)
    AC003038, AF521885, AI057363, FN356975
    Consensus CDS
    CCDS32966.1
    UniProtKB/Swiss-Prot
    Q86VD7
    UniProtKB/TrEMBL
    A0A024R7K2, Q8NHH2
    Related
    ENSP00000326693.6, OTTHUMP00000271301, ENST00000318596.7, OTTHUMT00000465931
    Conserved Domains (1) summary
    cl28162
    Location:34295
    Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p12 Primary Assembly

    Range
    19063961..19113030
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005259861.3XP_005259918.1  mitochondrial coenzyme A transporter SLC25A42 isoform X2

    See identical proteins and their annotated locations for XP_005259918.1

    UniProtKB/Swiss-Prot
    Q86VD7
    UniProtKB/TrEMBL
    A0A024R7K2
    Conserved Domains (1) summary
    cl28162
    Location:34295
    Mito_carr; Mitochondrial carrier protein
  2. XM_011527937.2XP_011526239.1  mitochondrial coenzyme A transporter SLC25A42 isoform X2

    See identical proteins and their annotated locations for XP_011526239.1

    UniProtKB/Swiss-Prot
    Q86VD7
    UniProtKB/TrEMBL
    A0A024R7K2
    Conserved Domains (1) summary
    cl28162
    Location:34295
    Mito_carr; Mitochondrial carrier protein
  3. XM_017026670.2XP_016882159.1  mitochondrial coenzyme A transporter SLC25A42 isoform X1

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