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ZNF615 zinc finger protein 615 [ Homo sapiens (human) ]

Gene ID: 284370, updated on 4-Jul-2021

Summary

Official Symbol
ZNF615provided by HGNC
Official Full Name
zinc finger protein 615provided by HGNC
Primary source
HGNC:HGNC:24740
See related
Ensembl:ENSG00000197619
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in prostate (RPKM 9.4), thyroid (RPKM 3.7) and 24 other tissues See more
Orthologs
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Genomic context

See ZNF615 in Genome Data Viewer
Location:
19q13.41
Exon count:
8
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (51991332..52008221, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (52494585..52511464, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 613 Neighboring gene ZNF350 antisense RNA 1 Neighboring gene zinc finger protein 350 Neighboring gene zinc finger protein 614 Neighboring gene uncharacterized LOC112268244 Neighboring gene zinc finger protein 432

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ33710, FLJ39372, DKFZp686O1554

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199324.2NP_001186253.1  zinc finger protein 615 isoform 1

    See identical proteins and their annotated locations for NP_001186253.1

    Status: VALIDATED

    Source sequence(s)
    AC011460, BC053884, BC112961, BX647556, DA095942
    Consensus CDS
    CCDS59418.1
    UniProtKB/Swiss-Prot
    Q8N8J6
    Related
    ENSP00000471041.1, ENST00000598071.6
    Conserved Domains (5) summary
    smart00349
    Location:868
    KRAB; krueppel associated box
    COG5048
    Location:325729
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:426449
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001321317.2NP_001308246.1  zinc finger protein 615 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC011460, AK294977, BC053884, BX647556
    Consensus CDS
    CCDS82387.1
    UniProtKB/TrEMBL
    B4DH87, H9KV89
    Related
    ENSP00000375672.3, ENST00000391795.7
    Conserved Domains (5) summary
    smart00349
    Location:1373
    KRAB; krueppel associated box
    COG5048
    Location:319723
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:407427
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1352
    KRAB; KRAB box
    pfam13465
    Location:420443
    zf-H2C2_2; Zinc-finger double domain
  3. NM_001321318.2NP_001308247.1  zinc finger protein 615 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC011460, AC011468, AK128361, BX647556
    UniProtKB/Swiss-Prot
    Q8N8J6
    Conserved Domains (5) summary
    smart00349
    Location:464
    KRAB; krueppel associated box
    COG5048
    Location:321725
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:409429
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:443
    KRAB; KRAB box
    pfam13465
    Location:422445
    zf-H2C2_2; Zinc-finger double domain
  4. NM_001321319.2NP_001308248.1  zinc finger protein 615 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC011460, AC011468, BC112961, BX647556
    Consensus CDS
    CCDS59418.1
    UniProtKB/Swiss-Prot
    Q8N8J6
    Related
    ENSP00000471549.1, ENST00000594083.5
    Conserved Domains (5) summary
    smart00349
    Location:868
    KRAB; krueppel associated box
    COG5048
    Location:325729
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:426449
    zf-H2C2_2; Zinc-finger double domain
  5. NM_001321320.2NP_001308249.1  zinc finger protein 615 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC011460, AC011468, BX647556, DA119086, DB235427, DB290987
    Consensus CDS
    CCDS12846.1
    UniProtKB/Swiss-Prot
    Q8N8J6
    Conserved Domains (5) summary
    smart00349
    Location:868
    KRAB; krueppel associated box
    COG5048
    Location:314718
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:402422
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:415438
    zf-H2C2_2; Zinc-finger double domain
  6. NM_001321321.2NP_001308250.1  zinc finger protein 615 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC011460, AC011468, BX647556, DA322276, DA802380
    Consensus CDS
    CCDS59418.1
    UniProtKB/Swiss-Prot
    Q8N8J6
    Related
    ENSP00000483676.1, ENST00000618487.4
    Conserved Domains (5) summary
    smart00349
    Location:868
    KRAB; krueppel associated box
    COG5048
    Location:325729
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:426449
    zf-H2C2_2; Zinc-finger double domain
  7. NM_001321322.2NP_001308251.1  zinc finger protein 615 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC011460, BX647556, DA322276
    Conserved Domains (5) summary
    smart00349
    Location:868
    KRAB; krueppel associated box
    COG5048
    Location:321725
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:409429
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:422445
    zf-H2C2_2; Zinc-finger double domain
  8. NM_001321323.2NP_001308252.1  zinc finger protein 615 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC011460, BX647556, DA240372
    Conserved Domains (5) summary
    smart00349
    Location:1373
    KRAB; krueppel associated box
    COG5048
    Location:330734
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:418438
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1352
    KRAB; KRAB box
    pfam13465
    Location:431454
    zf-H2C2_2; Zinc-finger double domain
  9. NM_198480.4NP_940882.3  zinc finger protein 615 isoform 2

    See identical proteins and their annotated locations for NP_940882.3

    Status: VALIDATED

    Source sequence(s)
    AC011460, AK094071, BC105100, BX647556, DA236166, DA244381
    Consensus CDS
    CCDS12846.1
    UniProtKB/Swiss-Prot
    Q8N8J6
    Related
    ENSP00000365906.4, ENST00000376716.9
    Conserved Domains (5) summary
    smart00349
    Location:868
    KRAB; krueppel associated box
    COG5048
    Location:314718
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:402422
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:415438
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    51991332..52008221 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017026648.2XP_016882137.1  zinc finger protein 615 isoform X1

    UniProtKB/Swiss-Prot
    Q8N8J6
    Conserved Domains (5) summary
    smart00349
    Location:868
    KRAB; krueppel associated box
    COG5048
    Location:314718
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:402422
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:415438
    zf-H2C2_2; Zinc-finger double domain
  2. XM_017026649.2XP_016882138.1  zinc finger protein 615 isoform X1

    UniProtKB/Swiss-Prot
    Q8N8J6
    Conserved Domains (5) summary
    smart00349
    Location:868
    KRAB; krueppel associated box
    COG5048
    Location:314718
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:402422
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:415438
    zf-H2C2_2; Zinc-finger double domain
  3. XM_017026651.2XP_016882140.1  zinc finger protein 615 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:206610
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:294314
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:307330
    zf-H2C2_2; Zinc-finger double domain
  4. XM_011526829.2XP_011525131.1  zinc finger protein 615 isoform X2

    See identical proteins and their annotated locations for XP_011525131.1

    Conserved Domains (3) summary
    COG5048
    Location:206610
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:294314
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:307330
    zf-H2C2_2; Zinc-finger double domain
  5. XM_011526830.1XP_011525132.1  zinc finger protein 615 isoform X2

    See identical proteins and their annotated locations for XP_011525132.1

    Conserved Domains (3) summary
    COG5048
    Location:206610
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:294314
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:307330
    zf-H2C2_2; Zinc-finger double domain
  6. XM_017026650.2XP_016882139.1  zinc finger protein 615 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:206610
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:294314
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:307330
    zf-H2C2_2; Zinc-finger double domain
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