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ZNF575 zinc finger protein 575 [ Homo sapiens (human) ]

Gene ID: 284346, updated on 2-Nov-2024

Summary

Official Symbol
ZNF575provided by HGNC
Official Full Name
zinc finger protein 575provided by HGNC
Primary source
HGNC:HGNC:27606
See related
Ensembl:ENSG00000176472 AllianceGenome:HGNC:27606
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in colon (RPKM 2.0), fat (RPKM 1.6) and 24 other tissues See more
Orthologs
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Genomic context

See ZNF575 in Genome Data Viewer
Location:
19q13.31
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (43530835..43536087)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (46352369..46357622)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (44037340..44040239)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene pleckstrin homology like domain family B member 3 Neighboring gene Sharpr-MPRA regulatory region 2471 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:44008034-44008556 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10719 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:44017305-44017805 Neighboring gene ETHE1 persulfide dioxygenase Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10720 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:44029999-44030504 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:44030505-44031009 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10721 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:44035307-44035478 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10722 Neighboring gene X-ray repair cross complementing 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:44067237-44067737 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10723 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14726 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:44080053-44080579 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:44080580-44081105 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14727 Neighboring gene phospholipase A2 inhibitor and LY6/PLAUR domain containing Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14728 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:44098910-44099706 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14729 Neighboring gene immunity related GTPase Q

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Clone Names

  • FLJ32567

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001394237.1NP_001381166.1  zinc finger protein 575

    Status: VALIDATED

    Source sequence(s)
    AC018758
    Consensus CDS
    CCDS12623.1
    UniProtKB/Swiss-Prot
    B4DX54, Q86XF7
    Related
    ENSP00000472578.1, ENST00000601282.1
    Conserved Domains (2) summary
    PHA03247
    Location:6211
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:93113
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_174945.3NP_777605.1  zinc finger protein 575

    See identical proteins and their annotated locations for NP_777605.1

    Status: VALIDATED

    Source sequence(s)
    AC018758
    Consensus CDS
    CCDS12623.1
    UniProtKB/Swiss-Prot
    B4DX54, Q86XF7
    Related
    ENSP00000315870.4, ENST00000314228.10
    Conserved Domains (2) summary
    PHA03247
    Location:6211
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:93113
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    43530835..43536087
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011526793.4XP_011525095.1  zinc finger protein 575 isoform X1

    See identical proteins and their annotated locations for XP_011525095.1

    UniProtKB/Swiss-Prot
    B4DX54, Q86XF7
    Conserved Domains (2) summary
    PHA03247
    Location:6211
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:93113
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_047438637.1XP_047294593.1  zinc finger protein 575 isoform X1

    UniProtKB/Swiss-Prot
    B4DX54, Q86XF7
    Related
    ENSP00000471083.2, ENST00000598080.6

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    46352369..46357622
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054320626.1XP_054176601.1  zinc finger protein 575 isoform X1

    UniProtKB/Swiss-Prot
    B4DX54, Q86XF7