Format

Send to:

Choose Destination

TMEM145 transmembrane protein 145 [ Homo sapiens (human) ]

Gene ID: 284339, updated on 23-Nov-2021

Summary

Official Symbol
TMEM145provided by HGNC
Official Full Name
transmembrane protein 145provided by HGNC
Primary source
HGNC:HGNC:26912
See related
Ensembl:ENSG00000167619
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in brain (RPKM 11.6), adrenal (RPKM 1.6) and 1 other tissue See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See TMEM145 in Genome Data Viewer
Location:
19q13.2
Exon count:
15
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (42313309..42325064)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (42817461..42829216)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ZFP161 motif-containing MPRA enhancer 284/285 Neighboring gene capicua transcriptional repressor Neighboring gene platelet activating factor acetylhydrolase 1b catalytic subunit 3 Neighboring gene proline rich 19 Neighboring gene multiple EGF like domains 8 Neighboring gene microRNA 8077 Neighboring gene cornifelin

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Clone Names

  • FLJ90805

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in response to pheromone IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001366910.1NP_001353839.1  transmembrane protein 145 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AC024078
    Related
    ENSP00000500040.1, ENST00000673187.1
    Conserved Domains (1) summary
    pfam10192
    Location:157411
    GpcrRhopsn4; Rhodopsin-like GPCR transmembrane domain
  2. NM_173633.3NP_775904.2  transmembrane protein 145 isoform 2 precursor

    See identical proteins and their annotated locations for NP_775904.2

    Status: VALIDATED

    Source sequence(s)
    AC024078, AK075286, DA694683
    Consensus CDS
    CCDS12603.1
    UniProtKB/Swiss-Prot
    Q8NBT3
    Related
    ENSP00000301204.2, ENST00000301204.8
    Conserved Domains (1) summary
    pfam10192
    Location:143397
    GpcrRhopsn4; Rhodopsin-like GPCR transmembrane domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    42313309..42325064
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011526792.1XP_011525094.1  transmembrane protein 145 isoform X3

    Conserved Domains (1) summary
    cl21735
    Location:157314
    Lung_7-TM_R; Lung seven transmembrane receptor
  2. XM_011526791.3XP_011525093.1  transmembrane protein 145 isoform X2

    Conserved Domains (2) summary
    pfam10192
    Location:143397
    GpcrRhopsn4; Rhodopsin-like GPCR transmembrane domain
    pfam17037
    Location:418546
    CBP_BcsO; Cellulose biosynthesis protein BcsO
Support Center