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BOD1L2 biorientation of chromosomes in cell division 1 like 2 [ Homo sapiens (human) ]

Gene ID: 284257, updated on 17-Jun-2024

Summary

Official Symbol
BOD1L2provided by HGNC
Official Full Name
biorientation of chromosomes in cell division 1 like 2provided by HGNC
Primary source
HGNC:HGNC:28505
See related
Ensembl:ENSG00000228075 AllianceGenome:HGNC:28505
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BOD1P; FAM44C
Summary
Predicted to enable protein phosphatase 2A binding activity and protein phosphatase inhibitor activity. Predicted to be involved in negative regulation of phosphoprotein phosphatase activity. Predicted to be located in cytoplasm. Predicted to be part of outer kinetochore. Predicted to be active in centrosome; spindle microtubule; and spindle pole. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See BOD1L2 in Genome Data Viewer
Location:
18q21.31
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (57147087..57150410)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (57349948..57353271)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (54814318..54817641)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372136 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13366 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:54728921-54729810 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr18:54731909-54732444 Neighboring gene long intergenic non-protein coding RNA, regulator of reprogramming Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr18:54738769-54739482 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr18:54739483-54740196 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:54743705-54744654 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr18:54744655-54745604 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr18:54745605-54746553 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:54814487-54815082 Neighboring gene long intergenic non-protein coding RNA 2565 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr18:54877070-54878269 Neighboring gene RNA, U6 small nuclear 737, pseudogene

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC33608

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cell division IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
biorientation of chromosomes in cell division protein 1-like 2
Names
biorientation of chromosomes in cell division 1 pseudogene
biorientation of chromosomes in cell division protein 1 pseudogene
family with sequence similarity 44, member C
putative biorientation of chromosomes in cell division protein 1 pseudogene
putative biorientation of chromosomes in cell division protein 1-like 2
putative protein FAM44C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001257964.2NP_001244893.1  biorientation of chromosomes in cell division protein 1-like 2

    See identical proteins and their annotated locations for NP_001244893.1

    Status: VALIDATED

    Source sequence(s)
    AC100775
    Consensus CDS
    CCDS59322.1
    UniProtKB/Swiss-Prot
    B3KXU4, Q8IYS8, Q8WW13
    UniProtKB/TrEMBL
    B4DX39
    Related
    ENSP00000467843.1, ENST00000585477.2
    Conserved Domains (1) summary
    pfam05205
    Location:42135
    COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    57147087..57150410
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    57349948..57353271
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_005659.3: Suppressed sequence

    Description
    NG_005659.3: This RefSeq was permanently suppressed because it is now thought that this gene represents a transcribed pseudogene.
  2. NG_026335.1: Suppressed sequence

    Description
    NG_026335.1: This RefSeq was permanently suppressed because it is now thought that this pseudogene is transcribed.
  3. NM_175906.2: Suppressed sequence

    Description
    NM_175906.2: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
  4. NR_033372.1: Suppressed sequence

    Description
    NR_033372.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.