U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

FAM171A2 family with sequence similarity 171 member A2 [ Homo sapiens (human) ]

Gene ID: 284069, updated on 22-Sep-2022

Summary

Official Symbol
FAM171A2provided by HGNC
Official Full Name
family with sequence similarity 171 member A2provided by HGNC
Primary source
HGNC:HGNC:30480
See related
Ensembl:ENSG00000161682 AllianceGenome:HGNC:30480
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in brain (RPKM 5.8), ovary (RPKM 1.4) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See FAM171A2 in Genome Data Viewer
Location:
17q21.31
Exon count:
9
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (44353215..44363853, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (45207214..45217873, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (42430583..42441221, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904009 Neighboring gene CRISPRi-validated cis-regulatory element chr17.2878 Neighboring gene granulin precursor Neighboring gene ribosomal protein L7 like 1 pseudogene 5 Neighboring gene integrin subunit alpha 2b

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC34829

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198475.3NP_940877.2  protein FAM171A2 precursor

    See identical proteins and their annotated locations for NP_940877.2

    Status: VALIDATED

    Source sequence(s)
    AC003043
    Consensus CDS
    CCDS45701.1
    UniProtKB/Swiss-Prot
    A8MQB4, A8MVW0
    Related
    ENSP00000293443.6, ENST00000293443.12
    Conserved Domains (1) summary
    pfam10577
    Location:41824
    UPF0560; uncharacterized protein family UPF0560

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    44353215..44363853 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017024490.2XP_016879979.1  protein FAM171A2 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    45207214..45217873 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)