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UQCC4 ubiquinol-cytochrome c reductase complex assembly factor 4 [ Homo sapiens (human) ]

Gene ID: 283951, updated on 27-Sep-2022

Summary

Official Symbol
UQCC4provided by HGNC
Official Full Name
ubiquinol-cytochrome c reductase complex assembly factor 4provided by HGNC
Primary source
HGNC:HGNC:27558
See related
Ensembl:ENSG00000174109 AllianceGenome:HGNC:27558
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
URLC5; gs103; CCSMST1; C16orf91
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal (RPKM 6.1), brain (RPKM 5.9) and 25 other tissues See more
Orthologs
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Genomic context

See UQCC4 in Genome Data Viewer
Location:
16p13.3
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (1419752..1420747, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (1434364..1435359, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (1469753..1470748, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene unk like zinc finger Neighboring gene tight junction protein 1 pseudogene 1 Neighboring gene uncharacterized LOC101929440 Neighboring gene nonconserved acetylation island sequence 122 enhancer Neighboring gene uncharacterized LOC105371044

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC104723

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein CCSMST1
Names
cattle cerebrum and skeletal muscle-specific protein 1 family member
up-regulated in lung cancer 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001272051.2NP_001258980.1  protein CCSMST1 precursor

    See identical proteins and their annotated locations for NP_001258980.1

    Status: VALIDATED

    Source sequence(s)
    AW014549, BC023590, BQ962326
    Consensus CDS
    CCDS61789.1
    UniProtKB/Swiss-Prot
    Q4G0I0, Q96RZ0
    UniProtKB/TrEMBL
    A0A0A8K8N9
    Related
    ENSP00000413100.2, ENST00000442039.3
    Conserved Domains (1) summary
    pfam15013
    Location:47119
    CCSMST1; CCSMST1 family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    1419752..1420747 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    1434364..1435359 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001010878.1: Suppressed sequence

    Description
    NM_001010878.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.