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C16orf54 chromosome 16 open reading frame 54 [ Homo sapiens (human) ]

Gene ID: 283897, updated on 18-Aug-2020

Summary

Official Symbol
C16orf54provided by HGNC
Official Full Name
chromosome 16 open reading frame 54provided by HGNC
Primary source
HGNC:HGNC:26649
See related
Ensembl:ENSG00000185905
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in bone marrow (RPKM 12.2), lymph node (RPKM 8.7) and 11 other tissues See more
Orthologs

Genomic context

See C16orf54 in Genome Data Viewer
Location:
16p11.2
Exon count:
2
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (29742463..29745990, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (29753784..29757340, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chr16.2261 Neighboring gene RN7SK pseudogene 127 Neighboring gene zymogen granule protein 16 Neighboring gene uncharacterized LOC105371167

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Replication interactions

Interaction Pubs
HIV-1 infection (VSV-G pseudotyped) of CEMT4 T cells downregulates plasma membrane expression of C16orf54 PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ35681, MGC129957, MGC129958

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane protein C16orf54

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175900.4NP_787096.2  transmembrane protein C16orf54

    See identical proteins and their annotated locations for NP_787096.2

    Status: VALIDATED

    Source sequence(s)
    AC009133, BC025741, BC104466, DA427069
    Consensus CDS
    CCDS10652.1
    UniProtKB/Swiss-Prot
    Q6UWD8
    Related
    ENSP00000327506.3, ENST00000329410.4
    Conserved Domains (1) summary
    pfam15755
    Location:1223
    DUF4689; Domain of unknown function (DUF4689)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    29742463..29745990 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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