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ZNF740 zinc finger protein 740 [ Homo sapiens (human) ]

Gene ID: 283337, updated on 3-May-2020

Summary

Official Symbol
ZNF740provided by HGNC
Official Full Name
zinc finger protein 740provided by HGNC
Primary source
HGNC:HGNC:27465
See related
Ensembl:ENSG00000139651
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Zfp740
Expression
Ubiquitous expression in thyroid (RPKM 8.1), ovary (RPKM 7.3) and 25 other tissues See more
Orthologs

Genomic context

See ZNF740 in Genome Data Viewer
Location:
12q13.13
Exon count:
8
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (53180715..53195142)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (53574535..53584654)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene HIG1 hypoxia inducible domain family member 1A pseudogene 1 Neighboring gene eukaryotic translation initiation factor 4A1 pseudogene 4 Neighboring gene cysteine sulfinic acid decarboxylase Neighboring gene integrin subunit beta 7 Neighboring gene retinoic acid receptor gamma Neighboring gene major facilitator superfamily domain containing 5

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC61706

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Inferred from Sequence Alignment
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nuclear chromatin ISA
Inferred from Sequence Alignment
more info
 
nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 740
Names
oriLyt TD-element-binding protein 7

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004304.4NP_001004304.1  zinc finger protein 740

    See identical proteins and their annotated locations for NP_001004304.1

    Status: VALIDATED

    Source sequence(s)
    AC073573, AK091946, BC053557
    Consensus CDS
    CCDS44896.1
    UniProtKB/Swiss-Prot
    Q8NDX6
    Related
    ENSP00000409463.2, ENST00000416904.5
    Conserved Domains (2) summary
    sd00017
    Location:103123
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:115140
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    53180715..53195142
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017019181.1XP_016874670.1  zinc finger protein 740 isoform X3

    Conserved Domains (2) summary
    sd00017
    Location:103123
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:115140
    zf-H2C2_2; Zinc-finger double domain
  2. XM_011538194.2XP_011536496.1  zinc finger protein 740 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:96178
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:103123
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:115140
    zf-H2C2_2; Zinc-finger double domain
  3. XM_006719344.2XP_006719407.1  zinc finger protein 740 isoform X1

    Conserved Domains (3) summary
    COG5048
    Location:96178
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:103123
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:115140
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. XR_001748655.1 RNA Sequence

  2. XR_944519.1 RNA Sequence

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